# Molecular Biology and Immunopathology Core

> **NIH NIH P20** · LOUISIANA STATE UNIV A&M COL BATON ROUGE · 2021 · $296,317

## Abstract

Summary Molecular Biology Immunopathology Core.
The proposed Center for Pre-Clinical Cancer Research (Cancer COBRE) at Louisiana State University (LSU)
focuses on elucidating molecular and cellular mechanisms of human cancer using specialized disease models
that are predictive of disease in humans. The Cancer COBRE will focus on devastating human cancers that have
poor treatment outcome in patients in need of novel therapeutic strategies. The proposed projects led by highly
Promising Junior Investigators (PJIs) require the application of advanced molecular biological and
immunopathological principles, methods and particularly advances in genomics, transcriptomics and proteomics,
immunology and pathology to delineate key cellular mechanisms for each specific cancer necessitating access
to state-of-the-art equipment and technical expertise. The Molecular Biology and Immunopathology Core
(MBIPC) has been created to leverage and expand the resources and expertise of the Division of Biotechnology
and Molecular Medicine (BioMMED) at the LSU School of Veterinary Medicine (SVM), which administers six
Core Facilities: Gene Expression and Sequencing Laboratory (GeneLab), Viral Vectors Laboratory, Protein
Characterization and Purification laboratory (PCPL), which is also generates monospecific and monoclonal
antibodies to proteins of interest, the Small Animal Imaging Laboratory (SAIL) and the Molecular
Immunopathology laboratory (MIPL) that provides expertise in immunopathology and access to the SVM
Centralized Facilities (FACS and Pathology Cost Centers), and also provides expertise and access to bioimaging
and advanced immunofluorescence and electron microscopy. These laboratories are currently co-supported by
the Louisiana Biomedical Research Network (LBRN/INBRE), which also operates the LBRN Bioinformatics Core
in close collaboration with the LSU Center for Computation & Technology (CCT). The goal of MBIPC is to provide
and coordinate access to state of the advanced instrumentation and services and provide training in a broad
spectrum of fundamental and advanced molecular biology and immunopathology to all PJIs and other NIH-
funded investigators to achieve their research objectives. MBIPC has identified two specific aims:
Aim 1. To provide the Cancer COBRE and other NIH-funded investigators with resources and expertise in
molecular and cell biology and immunopathology including instrumentation, technical support, consultation and
training, and assistance in developing new methodologies.
Aim 2: To organize, coordinate, and facilitate interactions among COBRE investigators and work collaboratively
to develop and use new technologies and assays, and train PJIs, faculty, staff, and students in advanced
molecular biology and immunopathology technologies.

## Key facts

- **NIH application ID:** 10104815
- **Project number:** 1P20GM135000-01A1
- **Recipient organization:** LOUISIANA STATE UNIV A&M COL BATON ROUGE
- **Principal Investigator:** Konstantin G Kousoulas
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $296,317
- **Award type:** 1
- **Project period:** 2021-03-01 → 2026-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10104815

## Citation

> US National Institutes of Health, RePORTER application 10104815, Molecular Biology and Immunopathology Core (1P20GM135000-01A1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10104815. Licensed CC0.

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