# Comparative effectiveness of mind-body interventions for osteoarthritis - individual patient data network meta-analysis

> **NIH NIH K23** · TUFTS MEDICAL CENTER · 2021 · $167,400

## Abstract

Project Summary
Dr. Bannuru’s long-term career goal is to combine expertise in clinical medicine, clinical research and mind-
body medicine, in a way that allows him to identify key clinical opportunities, and to lead multi-disciplinary
research to develop models that allow for a more flexible evidence-base for the practice of personalized
medicine. Dr. Bannuru received postdoctoral fellowship (T32 & F32) to train in clinical research and gain an
introduction to comparative effectiveness research. The overall objective of this K23 proposal is to provide Dr.
Bannuru protected time to acquire advanced skills and experience in mind-body medicine research necessary
to achieve his long-term goal. The proposed career development plan will enable Dr. Bannuru to achieve his
immediate career goal of refining and consolidating his research skills in the development of predictive models
and risk stratification models, extending methods he has employed on one level (study level) to another level
(patient-level) data, learning other modeling techniques (such as individual patient data (IPD) analysis), and
increasing his fund of knowledge regarding Complementary and Integrative Medicine (CIM) so that the mind-
body therapy evidence-base developed is more applicable to individual patients. Career Development
Activities: This proposed plan builds logically on his training as a physician, as well as his research education
and prior work as part of his F32. With his mentors, Dr. Bannuru has crafted a comprehensive training plan
consistent with his career goals. The plan will engage him in robust training activities including: 1) structured
mentorship; 2) specific training in mind-body medicine research; 3) constructing and managing the database
for IPD analysis; 4) advanced training in IPD network meta-analysis, predictive modeling and responsive sub-
group analysis; 5) research project; 6) workshops and seminars; 7) scientific writing and grantsmanship; and 8)
responsible conduct of research. Dr. Bannuru has assembled a team of mentors with complementary expertise
in the key areas of mind-body medicine, osteoarthritis, IPD methodology, predictive analytics and statistics. In
addition to providing scientific guidance, his mentors will also offer career advice and facilitate new research
collaborations which will allow him to broaden his professional network. Environment: Dr. Bannuru will benefit
from the wealth of resources available to young investigators at the Tufts Medical Center. His association with
Tufts Center for Complementary and Integrative Medicine, Tufts Clinical and Translational Science Institute
and Brown University Evidence Practice Center provides an ideal environment for interaction with well-known
researchers in the field of mind-body medicine and comparative effectiveness research which, going forward
will help him to enhance his expertise in state-of-the-art research methods, and develop into an independent
investigator. Research: Osteoarthri...

## Key facts

- **NIH application ID:** 10106587
- **Project number:** 5K23AT009374-05
- **Recipient organization:** TUFTS MEDICAL CENTER
- **Principal Investigator:** Raveendhara Reddy Bannuru
- **Activity code:** K23 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $167,400
- **Award type:** 5
- **Project period:** 2017-03-01 → 2022-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10106587

## Citation

> US National Institutes of Health, RePORTER application 10106587, Comparative effectiveness of mind-body interventions for osteoarthritis - individual patient data network meta-analysis (5K23AT009374-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10106587. Licensed CC0.

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