# Neuroimaging and Neuromodulation Core

> **NIH NIH P20** · BUTLER HOSPITAL (PROVIDENCE, RI) · 2021 · $286,601

## Abstract

Project Summary
The research projects proposed in the COBRE Center for Neuromodulation involve a broad
range of neuroimaging and neuromodulatory methods, and often involving clinical participants
or those with neuropsychiatric pathology. Neuroimaging methods include task- and resting state
MRI, and stimulation methods include single pulse and repetitive transcranial magnetic
stimulation or transcranial direct stimulation. These techniques are, by their nature, highly
complex and require significant technical mastery to successful deploy them in clinical
populations. This problem is significantly prominent for relatively junior investigators or those
new to these fields. The function of this COBRE Neuroimaging and Neuromodulation Core
(NNC) is to provide ongoing expert support, training, assistance and advice to the COBRE
project leaders in the wide-range of practical aspects of implementation, data collection, and
management related to these methods. Therefore, the Specific Aims of the NNC are to (1)
provide support, training and assistance to COBRE Project Leaders (PLs) to promote and
facilitate the acquisition of high quality neuroimaging data; (2) provide support, training
and assistance to COBRE PLs to facilitate the application of high quality
neuromodulation; and (3) to establish core resources with a trajectory toward self-
sustaining and enduring status that will serve the larger neuromodulation research
community in Rhode Island. To meet these aims, the NNC of this COBRE Center will provide
highly specialized expertise, hands-on training, educational forums, and assistance in numerous
aspects of protocol implementation, data acquisition and resources as required to meet the aims
in each COBRE project and the unique needs of neuromodulation investigators. It will offer
critical laboratory space, equipment, infrastructure, and medical supervision needed by
investigators working with clinical samples. By meeting these goals, the NNC will (a) accelerate
the pace of high-quality mechanism-oriented COBRE research; (b) facilitate the use of safe and
scientifically rigorous stimulation protocols; (3) ensure the availability and accessibility of high
quality research infrastructure over time for COBRE investigators and the broader Rhode Island
research community.

## Key facts

- **NIH application ID:** 10106645
- **Project number:** 5P20GM130452-03
- **Recipient organization:** BUTLER HOSPITAL (PROVIDENCE, RI)
- **Principal Investigator:** LINDA L CARPENTER
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $286,601
- **Award type:** 5
- **Project period:** 2019-03-01 → 2024-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10106645

## Citation

> US National Institutes of Health, RePORTER application 10106645, Neuroimaging and Neuromodulation Core (5P20GM130452-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10106645. Licensed CC0.

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