# Scientific Core C Mouse Resources

> **NIH NIH P01** · INDIANA UNIVERSITY INDIANAPOLIS · 2021 · $393,785

## Abstract

ABSTRACT
Core C is the Mouse Resources Core. All three Projects will make extensive use of genetically modified mice
for their proposed experiments. The purpose of Core C is to provide a centralized localization of the animals,
sharing of common breeding stocks, and uniform performance of genotype analyses, which will
maximize efficiency and minimize costs associated with the production and maintenance of the mice
needed for the proposed experiments. Specific activities of the Core C include (1) assistance in the
generation of new genetically modified mouse models; (2) establishment and maintenance of breeding
stocks; (3) generation of timed pregnancies; (4) generation of postnatal experimental animals; (5) delivery
of experimental animals to the appropriate laboratory for use; (6) distribution of genetically modified mouse
models. Core C personnel are well-trained in all aspects of the services to be provided. Given the heavy
reliance on genetically modified animals and the proven performance of the Core personnel, the
importance of Core C to the success of the Program Project Grant application cannot be overstated.
RELEVANCE
The major benefit of this Mouse Resources Core to these three Projects is to facilitate development of new
animal models and efficient usage of existing animal models of human disease thereby accelerating basic
discovery. The benefit of this Core to society is to maximize efficiency and minimize the costs associated with
usage of animal models of human disease.

## Key facts

- **NIH application ID:** 10111563
- **Project number:** 5P01HL134599-05
- **Recipient organization:** INDIANA UNIVERSITY INDIANAPOLIS
- **Principal Investigator:** Lei Wei
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $393,785
- **Award type:** 5
- **Project period:** 2017-02-15 → 2023-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10111563

## Citation

> US National Institutes of Health, RePORTER application 10111563, Scientific Core C Mouse Resources (5P01HL134599-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10111563. Licensed CC0.

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