# Development of Allosteric Dihydrofolate Reductase Inhibitors: Exploration of a Novel Inhibitory Mechanism for a Validated Antibiotic Target

> **NIH NIH R15** · VILLANOVA UNIVERSITY · 2021 · $340,871


## Key facts

- **NIH application ID:** 10113254
- **Project number:** 1R15GM140412-01
- **Recipient organization:** VILLANOVA UNIVERSITY
- **Principal Investigator:** Matthew C O'Reilly
- **Activity code:** R15 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $340,871
- **Award type:** 1
- **Project period:** 2021-03-02 → 2025-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10113254

## Citation

> US National Institutes of Health, RePORTER application 10113254, Development of Allosteric Dihydrofolate Reductase Inhibitors: Exploration of a Novel Inhibitory Mechanism for a Validated Antibiotic Target (1R15GM140412-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10113254. Licensed CC0.

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*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
