# Pathology Research Shared Resource

> **NIH NIH P30** · MAYO CLINIC ROCHESTER · 2021 · $112,199

## Abstract

PATHOLOGY RESEARCH SHARED RESOURCE PROJECT SUMMARY
The Pathology Research Shared Resource (PRC) provides histological and related tissue-based services
across the enterprise to Mayo Clinic Cancer Center (MCCC) members at Mayo Clinic in Rochester, MN
(MCR), at Mayo Clinic in Arizona (MCA), and at Mayo Clinic in Florida (MCF). PRC works with site based
resources to standardize practices across the enterprise. The services include preparation of histology slides
for microscopy, tissue microarray construction, immunostaining, digital image capture and analysis, and
preparation of tissues for subsequent nucleic acid or protein extraction. A team of cytotechnologists assist with
morphologic interpretation of slides, choosing slides and blocks for tissue microarrays, and analysis of
microscopic images. PRC provides these services to research and clinical investigators at an affordable cost
with reasonable turnaround times. The majority of the services are performed using clinical diagnostic tissues
that are formalin fixed and paraffin embedded, allowing MCCC members to take advantage of the wealth of
clinical materials for biomarker discovery and validation. PRC also performs services on fresh tissues, animal
tissues, and tissue-cultured cells to facilitate translation of basic biology to clinical relevance. PRC functions
within a College of American Pathologists (CAP)-accredited quality system to provide consistent services
performed according to laboratory standard operating procedures. The services provided by PRC have been
vital to MCCC research at Mayo Clinic, providing members with state of the art services that would be difficult
to maintain in the laboratories of individual investigators. In addition, many investigators who use PRC are
epidemiologists and bioinformaticians in the MCCC Genetic Epidemiology & Risk Assessment Program
(GERA), who may not have laboratory space of their own.

## Key facts

- **NIH application ID:** 10113594
- **Project number:** 5P30CA015083-47
- **Recipient organization:** MAYO CLINIC ROCHESTER
- **Principal Investigator:** THOMAS J FLOTTE
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $112,199
- **Award type:** 5
- **Project period:** 1997-04-25 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10113594

## Citation

> US National Institutes of Health, RePORTER application 10113594, Pathology Research Shared Resource (5P30CA015083-47). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10113594. Licensed CC0.

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