# Technology Enhanced Self-Management Interventions for Fatigue and Pain: The Symptoms Self Management Center

> **NIH NIH P20** · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2020 · $200,055

## Abstract

PROJECT SUMMARY/ABSTRACT
The goal of this study within the supplement is to test the feasibility of a self-managed (SM), electronic/mobile
Health (e/mHealth) yoga intervention for reducing stress symptoms (burden) in older caregivers (CG) of people
with Alzheimer’s Disease and related dementia’s (PWD). CG burden can exacerbate a myriad of physical and
psychosocial comorbidities in CGs as well as PWD neuropsychiatric symptoms. These effects may be further
amplified in older CG with underlying health concerns or those who are not able to access programs for
effective management of their own medical or self-care needs. Low-impact physical activities such as gentle
Yoga (GY) have shown positive effects on mood and symptoms of pain and fatigue in older community
dwellers, and digital e/mHealth platforms have a great deal of potential to overcome financial and medical
barriers for the delivery SM stress interventions across demographic boundaries. In this study, we will examine
the feasibility of a 12-week e/mHealth gentle yoga+yogic breathing (GYYB) intervention for alleviating
symptoms of burden in aging CG of PWD (Aim 1); measure initial changes in stress and QoL indicators in CG
and PWD (post- vs. pre-intervention) to inform an adequately-powered, future efficacy trial (Aim 2), and;
establish a Dyadic Analysis Training Program for MUSC faculty within the College of Nursing and P20
Symptom Self-Management Center (SSMC) to support future research evaluating the influence of care-
recipient interactions on health outcomes (Aim 3). Feasibility will be assessed using the RE-AIM framework,
and will include measures such as recruitment, adherence, treatment satisfaction, attrition, and feedback for
intervention refinement. Data related to CG physical function, fatigue, depression, social isolation, loneliness,
relationship quality, burden, and stress biomarkers, as well as PWD and CG QoL, will be collected via daily
electronic practice logs and interviews at study beginning and end. Older (> 55 yrs. old) male and female CG
(N=20) of PWD regularly attending respite care (RCC) programs will be recruited from an existing study
population (R01 NR016466) participating in CG-RCC mealtime partnerships for improved PWD nutritional
outcomes. The HIPAA-compliant GYYB intervention will employ ‘tablets’ that allow CG to practice GYYB at
home by following along with recorded lessons. CG will initially be trained on the use of the tablet and proper
GYYB practices by the study coordinator (in-home), with weekly follow up (Skype/phone) for the duration of the
study. This investigation is ideally aligned with the aims of the parent SSMC (P20 NR016575) that are focused
on providing infrastructure and community-based resources for design and ecologically-valid testing of SM
interventions for individuals with chronic conditions.

## Key facts

- **NIH application ID:** 10115249
- **Project number:** 3P20NR016575-05S1
- **Recipient organization:** MEDICAL UNIVERSITY OF SOUTH CAROLINA
- **Principal Investigator:** Teresa J Kelechi
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $200,055
- **Award type:** 3
- **Project period:** 2016-07-27 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10115249

## Citation

> US National Institutes of Health, RePORTER application 10115249, Technology Enhanced Self-Management Interventions for Fatigue and Pain: The Symptoms Self Management Center (3P20NR016575-05S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10115249. Licensed CC0.

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