# Statistics Core

> **NIH NIH U10** · DANA-FARBER CANCER INST · 2021 · $3,399,802

## Abstract

The Statistics core activities are performed by the Biostatistics Center of the ECOG-ACRIN Statistics
and Data Management Center. The Biostatistics Center is responsible for design and analysis of all
ECOG-ACRIN studies. The Biostatistics Center has two components, SDMC-DFCI at the Dana-Farber
Cancer Institute, which has primary responsibility for therapeutic trials, and SDMC-Brown at Brown
University, which has primary responsibility for diagnostic and imaging studies. The Center includes a
group of highly experienced statisticians who are led by Drs. Constantine Gatsonis and Robert Gray.
The Center also has expertise in computational biology and has access to leading experts in this field
at DFCI and Brown.
The research structure of ECOG-ACRIN is organized into a number of scientific committees, which are
responsible for developing the Group's studies. ECOG-ACRIN statisticians are assigned to work with
specific scientific committees. They participate fully in the development of scientific directions and
collaborate on study concepts from the earliest discussions within the committees through the entire
process of development. Statisticians are responsible for developing statistical designs and analysis
plans to robustly address study's objectives. The Biostatistics Center is responsible for comprehensive
monitoring of all EA studies, including producing reports for monitoring study progress and safety and
producing confidential reports for the Data Safety Monitoring Committee, which include interim
analyses of outcome when appropriate. Statisticians also produce comprehensive reports on study
results at the completion of studies and collaborate with lead study investigators on the development of
manuscripts. Statisticians also collaborate with investigators on design and analysis of the ECOG-
ACRIN's translational science initiatives.

## Key facts

- **NIH application ID:** 10116337
- **Project number:** 5U10CA180794-08
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** ROBERT J GRAY
- **Activity code:** U10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $3,399,802
- **Award type:** 5
- **Project period:** 2014-04-29 → 2025-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10116337

## Citation

> US National Institutes of Health, RePORTER application 10116337, Statistics Core (5U10CA180794-08). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10116337. Licensed CC0.

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