# Mass Spectrometry Core

> **NIH NIH P20** · UNIVERSITY OF NEBRASKA MEDICAL CENTER · 2021 · $35,558

## Abstract

Project Summary/Abstract: Mass Spectrometry Core (Core 2)
The Mass Spectrometry Core (MSC) will collaborate with and support the project leaders within the Nebraska
Center for Molecular Target Discovery and Development in the identification and validation of new protein
targets for therapeutic drug treatment of cancers. The Core will utilize the newly established infrastructure and
analytical equipment from the Proteomics and Metabolomics Facility (PMF) of the Center for Biotechnology at
the University of Nebraska – Lincoln, which receives support from the Nebraska Research Initiative (NRI). The
new MSC core will be immediately operational to accept projects from the Project Leaders of the new Center.
The objective for the requested support for the MSC is to afford comprehensive services to the Project Leaders
and to introduce new analytical capabilities using the instrumentation and computing resources available. The
MSC will strive to remain state-of-the art, responding to and addressing the specific needs of the project aims
described by each Project Leader in the grant proposal. The Center will use the expertise and skills of the
leader Dr. Alvarez and Co-Investigator Dr. Naldrett in proteomics and mass spectrometry.
The major goals of the MSC are:
  to assist the Project Leaders with the experimental design and sample preparation required for the
 mass spectrometry-based experiments described in the grant proposal.
  to process and run samples requiring protein identification and/or quantification using mass
 spectrometry and other analytical tools.
  to optimize platforms for new PTMomics (post-translational modifications) capabilities using mass
spectrometry.
  to analyze the data acquired and assist with the interpretation of the results using the bioinformatic
 pipelines available in the core.
  to educate the Project Leaders and their students on best practice.
  to offer training of students involved in the projects on use of analytical equipment and analysis of mass
 spectrometry data.

## Key facts

- **NIH application ID:** 10117098
- **Project number:** 5P20GM121316-04
- **Recipient organization:** UNIVERSITY OF NEBRASKA MEDICAL CENTER
- **Principal Investigator:** Sophie Alvarez
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $35,558
- **Award type:** 5
- **Project period:** 2018-03-16 → 2023-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10117098

## Citation

> US National Institutes of Health, RePORTER application 10117098, Mass Spectrometry Core (5P20GM121316-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10117098. Licensed CC0.

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