The UTMB CTSA hub workforce development (WFD) objective is to create and sustain a diverse, robust multidisciplinary workforce with the skills, knowledge, and institutional environment necessary for continuous improvement in clinical and translational biomedical research. The new and existing competency-based educational and training opportunities described below are designed to be accessible, relevant and address learner-specific needs at all career stages, by being fully integrated with other U54, TL1 and KL2 workforce development components, and by engaging not only physician scientists and translational scientists, but also research coordinators, nurses, and other allied health professionals. Aligned with the strategic goals of our CTSA and domains of activity prioritized by NCATS, we will offer both on-site and on-line opportunities for training in team science (e.g., TeamMAPPS), team leadership (e.g., Leadership Challenge Program), medicaland bio-informatics (e.g., Foundations of Medical Informatics), entrepreneurship (e.g., TREx), communityengaged research, and the regulatory and ethical issues associated with human-subjects research and clinical trials (e.g.,Clinical Research Practicums). Our Clinical and Translational Research Pilot (CTRP) program brings together research resources and invests in them to advance team-based science that is aligned with institutional and national priorities. Our CTRP program continues to enrich new collaborations within our CTSA as well as to collaborate with other Universities and CTSA programs. Our goal is to award pilot projects that aptly reflect CTSA priority areas including translation of novel discoveries to improve patient care while understanding and addressing the organizational challenges underlying each stage of the translational process (i.e., implementation science). Towards these ends, our CTRP program will leverage the diverse strengths of our mentors, multidisciplinary teams and unique academic partnerships. Our clinical trials studio will assist investigators, as a frontdoor mechanism, to facilitate rigorous study design and application, by ensuing that our new clinical investigators have the essential skills to conduct their research using good clinical practice (GCP) standards. Additionally, the CTRP program will aim to include community engagement core in order to best disseminate translational findings and to expand studies into the rural areas. Each year, CTRP pilots will be evaluated and awarded in the following categories, 1) the pilot clinical trials [one - three per year] that represent successful translation for novel discovery of devices and therapeutics, 2) co-sponsored CTSA pilot grants with UTMB academic partners [two – four per year] and 3) to support a new MTT [one per year] that are designed to foster unique opportunities for scientific advancement and team growth. Additionally, vouchers will be administered with a special focus on new investigators to conduct feasibility...