The main functions of the Network Capacity component of the UTMB CTSA Hub are to support networkwide studies through our Trial Innovation Network (TIN) Hub Liaison Team and to link our hub with the CTSA Program Central Resources, including the Center for Leading Innovation and Collaboration (CLIC) and the Clinical Data to Health Coordinating Center (CD2H-CC). We will provide a nurturing environment to conduct high-quality, efficient, and regulation-compliant multi-site clinical trials in our areas of unique strength. We will continue to expand and enhance the clinical research and informatics infrastructure to provide more opportunities for our investigators to participate in TIN multi-site clinical trials and CLIC and CD2H-CC initiatives. We will also support the local development of multi-site studies to propose for dissemination by the TIN and will disseminate our Informatics discoveries and our innovative Team Science training programs nation-wide. We have strengthened and streamlined our clinical research infrastructure. We have integrated the Hub Liaison Team with the Office of Clinical Research, the single point of contact for all clinical studies. We have been working with our Informatics core to develop novel tools for clinical trial feasibility, patient recruitment, clinical data extraction and reporting, and multi-hub software interoperability. We have worked with Trials Today to establish a searchable customized UTMB trials website. The Hub Liaison Team will leverage the OCR and the informatics advancements to develop high-quality multi-site clinical trials with high recruitment yields at UTMB through its interactions with the TIN. The Network Capacity Specific Aims are: Aim 1. Optimize the UTMB Hub Liaison Team to improve access, rapidly respond to, and support CTSA Network TIN studies. Aim 2. Support and link the CTSA Program Central Resources with the UTMB Hub. Aim 3. Disseminate Team Science training to the CTSA Network. Effectiveness of the Network Capacity activities will be measured using common metrics as well as metrics locally developed using our continuous improvement methodology