# Pennington/Louisiana NORC - NOT-DK-20-009 Supplement

> **NIH NIH P30** · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2020 · $370,000

## Abstract

1. Project Summary
Recent parallel research advances in obesity and Alzheimer's disease and related disorders
(ADRD) have made it clear that there is a need for research at the interface of these two
disease areas. The Pennington / Louisiana NORC is perfectly situated to support efforts to
address knowledge gaps at this interface due to its substantial resources in metabolic
assessments. Pennington and nearby institutions are already doing ADRD-related research
and have faculty with interests at the obesity-ADRD interface. This is all what is needed to kick-
start innovative new obesity-ADRD research programs at the Pennington NORC using a strong
pilot and feasibility (P&F) funding program. Such P&F will allow to establish new techniques and
collect appropriate pilot data at the intersection between ADRD and energy balance. The goal
of this supplement is to fund 3 to 6 Pennington / Louisiana NORC P&F projects (each $40,000-
$80,000) focused at the interface between obesity, energy balance and ADRD. A range of
research from the molecular to human clinical levels will be supported, with an end goal of
enabling R01-level grants on interactions between nutrition and metabolism on one hand, and
the prevention and treatment of ADRD on the other. This effort could synergize existing
resources and thereby create novel advances in such areas as AD-pathology-related
unintentional weight loss; central insulin processing in ADRD; and mechanisms by which
exercise, calorie restriction, and time-restricted feeding modify AD risk.
2. Relevance
This Administrative Supplement is aimed at enhancing the amount and quality of research
within the Pennington NORC scientific scope that is directly relevant to Alzheimer's disease and
related disorders. The goal is to foster new research initiatives at the basic, clinical, and
population levels involving faculty with expertise in obesity and energy balance on one hand,
and ADRD on the other.

## Key facts

- **NIH application ID:** 10122683
- **Project number:** 3P30DK072476-15S2
- **Recipient organization:** LSU PENNINGTON BIOMEDICAL RESEARCH CTR
- **Principal Investigator:** Eric Ravussin
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $370,000
- **Award type:** 3
- **Project period:** 2005-07-01 → 2021-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10122683

## Citation

> US National Institutes of Health, RePORTER application 10122683, Pennington/Louisiana NORC - NOT-DK-20-009 Supplement (3P30DK072476-15S2). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10122683. Licensed CC0.

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