# Tailored Geriatric Assessment and Management for HIV Care Settings

> **NIH NIH K76** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2021 · $243,000

## Abstract

PROJECT SUMMARY/ABSTRACT
Due in large part to the successful development of antiretroviral therapy, adults with HIV infection are living
longer; in the United States, 47% of all people living with HIV are age 50 and older. This aging population
increasingly experiences multimorbidity, polypharmacy, and significant mental health and psychosocial
challenges. Older HIV-positive adults also experience a high frequency of geriatric conditions including falls,
frailty, and functional impairment. Geriatric assessment and management could help address this medical and
social complexity. Supporting a role for geriatric assessment, studies show that assessments can predict
hospitalization and mortality among older HIV-positive adults and geriatric conditions are associated with
poorer quality of life. Yet little is known on how to best integrate geriatric assessment and management in HIV
care settings. Strategies developed need to be efficient, able to be administered by non-geriatrics trained
clinicians, and also tailored to the unique aging issues that are influenced by HIV infection. Our proposal
addresses this knowledge gap by developing and testing a tailored Geriatric Assessment and Initial
Management guide focused on the needs of older HIV-positive adults, also referred to as G-AIM HIV.
Specifically, the objectives of this proposal are to 1) develop G-AIM HIV by incorporating patient and expert
perspectives on the most important geriatric assessment domains and initial management steps; 2) examine
HIV providers’ and staff attitudes towards G-AIM HIV and identify facilitators and barriers to its use; and 3) pilot
G-AIM HIV in two HIV outpatient settings to evaluate feasibility, acceptability and preliminary patient reported
outcomes such as quality of life. The objectives of this proposal support the career development activities of
the PI Dr. Meredith Greene focused on 1) Delphi methodology and stakeholder engagement, 2) qualitative
research methods, 3) intervention and clinical trial research with vulnerable populations, and 4) ongoing
leadership development. Dr. Greene will conduct all work at the University of California, San Francisco with an
exceptional mentoring team, led by Dr. Kenneth Covinsky. This K76 Beeson proposal will advance our
knowledge of how to integrate geriatric principles into HIV care to improve quality of life for older HIV-positive
adults. It will also provide advanced research skills and valuable data to launch Dr. Greene’s career as an
independent investigator and leader at the intersection of HIV and geriatric medicine.

## Key facts

- **NIH application ID:** 10125072
- **Project number:** 5K76AG064545-03
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** Meredith Greene
- **Activity code:** K76 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $243,000
- **Award type:** 5
- **Project period:** 2019-08-01 → 2024-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10125072

## Citation

> US National Institutes of Health, RePORTER application 10125072, Tailored Geriatric Assessment and Management for HIV Care Settings (5K76AG064545-03). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10125072. Licensed CC0.

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