# Examining the Role of Sleep Disturbances in Contributing to Health Risk Behaviors and Cardiometabolic Outcomes in Urban Native American Youth

> **NIH NIH R01** · RAND CORPORATION · 2021 · $645,349

## Abstract

Summary/Abstract
American Indian/Alaska Natives (AI/ANs) are one of the most at-risk racial/ethnic groups in the United States
for adverse cardiometabolic (CM) and behavior health (BH) outcomes, including cardiovascular disease (CVD),
diabetes, obesogenic behaviors and alcohol and other drug (AOD) use problems. Urban AI/ANs constitute over
two-thirds of the total AI/AN population and represent a highly disenfranchised and marginalized population
who may be at particular risk for CM and BH problems, but they have been significantly under-represented in
health studies. Adolescence is a critical developmental period for understanding the emergence of CM and BH
problems in vulnerable populations, as behavioral health risk factors often begin in adolescence and early
onset of CM dysregulation and BH problems can set the stage for widening health disparities that continue
long into adulthood. Sleep is an important but understudied risk factor that may contribute to CM and BH
problems in adolescents, but no prior studies have investigated the role of sleep in contributing to health
disparities in urban AI/AN youth. The current proposal builds on our team’s extensive experience conducting
research with urban AI/AN youth and provides a comprehensive, mixed method approach to investigate the
role of sleep disturbances in contributing to health behaviors and clinically relevant health outcomes in a
culturally sensitive, community-informed, and integrated framework. Specifically, this project incorporates a
longitudinal assessment of objectively and subjectively measured sleep, multiple dimensions of BH problems,
including tobacco, caffeine, and alcohol and other drug use, physical inactivity and electronic media use,
measured CM risk factors, and qualitative methods to better understand the social and cultural context of sleep
in urban AI/AN youth and the influence on downstream BH and CM problems. Outcomes from this work will
address several key knowledge gaps, which are crucial to better understand pervasive health disparities
among urban AI/AN youth, to identify which youth are most at risk, and to inform a future novel and culturally-
sensitive intervention within this underserved community.

## Key facts

- **NIH application ID:** 10128217
- **Project number:** 5R01MD012190-05
- **Recipient organization:** RAND CORPORATION
- **Principal Investigator:** ELIZABETH J. D'AMICO
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $645,349
- **Award type:** 5
- **Project period:** 2017-08-10 → 2024-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10128217

## Citation

> US National Institutes of Health, RePORTER application 10128217, Examining the Role of Sleep Disturbances in Contributing to Health Risk Behaviors and Cardiometabolic Outcomes in Urban Native American Youth (5R01MD012190-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10128217. Licensed CC0.

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