# Histology/Imaging Core C

> **NIH NIH P30** · CASE WESTERN RESERVE UNIVERSITY · 2021 · $237,042

## Abstract

HISTOLOGY/IMAGING CORE C PROJECT SUMMARY
The overall objective of the Histology/Imaging Core of the Cleveland DDRCC is to provide high-quality
morphologic analyses of the gastrointestinal and liver systems in experimental animal models and human GI
and liver-related pathologies. In addition, a major goal of the Histology/Imaging Core is to support new and
established investigators at Case Western Reserve University (CWRU) and the Cleveland Clinic Foundation
(CCF), who do not have a direct focus on digestive disease-related research, to enter this exciting field of
investigation and to encourage collaborations among DDRCC members working in the areas of digestive
inflammation and metabolism. The Histology/Imaging Core continues to be committed to provide basic and
fundamental histology, with pathology interpretation and semi-quantitative scoring, as well as
immunohistochemical (IHC) and immunofluorescence (IF) methodologies essential to GI- and liver-related
research, while at the same time implementing state-of-the-art technologies, such as digital pathology and small
animal imaging of DDRCC investigators’ preclinical and clinical studies. Importantly, Histology/Imaging Core
personnel will provide valuable expert consultation and facilitate the training and transfer of Core technologies
to DDRCC investigators and their lab members to enhance GI- and liver-related research programs at CWRU
and CCF. The specific aims for the DDRCC Histology/Imaging Core are: 1) Provide histological analysis and
scoring of GI & liver diseases; 2) Provide immunohistochemistry (IHC) and/or immunofluorescence (IF) staining;
3) Provide small animal imaging; 4) Provide digital pathology, image analysis, and photodocumentation, and 5)
Provide consultation, education, training, and provision of archival tissues. Through these aims, the Cleveland
DDRCC Histology/Imaging Core will facilitate the production of high-quality research in digestive diseases in a
cost-effective and time-efficient manner, and enhance the rate, depth, and breadth of research in Digestive
Inflammation/Tumorigenesis and Liver Disease/Metabolism throughout CWRU and CCF, leading to
advancement of scientific discoveries in this important field of investigation.

## Key facts

- **NIH application ID:** 10128433
- **Project number:** 5P30DK097948-07
- **Recipient organization:** CASE WESTERN RESERVE UNIVERSITY
- **Principal Investigator:** Theresa Torres Pizarro
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $237,042
- **Award type:** 5
- **Project period:** 2015-02-15 → 2025-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10128433

## Citation

> US National Institutes of Health, RePORTER application 10128433, Histology/Imaging Core C (5P30DK097948-07). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10128433. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*