# Alcohol Biomarkers and Clinical Outcomes in the MACS\WIHS Combined Cohort Study (MWCCS)  OAR Administrative Supplement

> **NIH NIH U01** · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2020 · $19,917

## Abstract

MACS/WIHS Combined Cohort Study (MWCCS) Administrative Supplement:
 Association of Alcohol Biomarkers with HIV and Clinical Outcomes
Abstract: Fund Year 2020 OAR Strategic Funds are requested to perform an objective
assessment of alcohol consumption in the MACS/WIHS Combined Cohort Study (MWCCS) by
testing urine and blood specimens for ethyl glucuronide (EIG) and phosphatidylethanol (PEth),
respectively.
Specimens will be collected on existing MACS and WIHS participants who enroll into the
MWCCS (n~4000) and in new MWCCS enrollees (n~1500) during CCS visits 101 and 102 in order
to better characterize alcohol use and their associations with HIV outcomes (i.e., antiretroviral
therapy [ART] adherence, viral suppression down to a single copy) and clinical outcomes (i.e.,
liver, cardiac, neurocognitive impairment). This supplement will support HIV/AIDS research that
falls under the following NIH high priority AIDS-designated topics: 1) HIV-associated
comorbidities ; and 2) cross-cutting areas including behavioral sciences, health disparities, and
training of the next generation of HIV investigators in substance use and comorbidities
research.

## Key facts

- **NIH application ID:** 10130715
- **Project number:** 3U01HL146204-02S1
- **Recipient organization:** ALBERT EINSTEIN COLLEGE OF MEDICINE
- **Principal Investigator:** Kathryn M. Anastos
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $19,917
- **Award type:** 3
- **Project period:** 2019-04-01 → 2026-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10130715

## Citation

> US National Institutes of Health, RePORTER application 10130715, Alcohol Biomarkers and Clinical Outcomes in the MACS\WIHS Combined Cohort Study (MWCCS)  OAR Administrative Supplement (3U01HL146204-02S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10130715. Licensed CC0.

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