# 2021 Mammalian DNA Repair Gordon Research Conference and Seminar

> **NIH NIH R13** · GORDON RESEARCH CONFERENCES · 2021 · $6,000

## Abstract

Summary of the 2021 Mammalian DNA Repair GRC and GRS
This 5-day GRC + 1.5-day GRS conference is focused on the research of genomic instability and its implications
in human diseases and therapies. The human genome is constantly threatened by DNA damage caused by
environmental insults and various cellular processes occurring in DNA. Common environmental mutagens
include radiation, aldehydes, and dioxins. Cellular processes such as DNA replication, transcription and mitosis
can also give rise to DNA damage when dysregulated. In normal cells, a multitude of DNA repair and DNA
damage response mechanisms successfully operate to maintain genomic stability. However, defects in these
mechanisms can result in diseases ranging from rare developmental and premature aging syndromes to
common cancers. This Mammalian DNA Repair Gordon Research Conference (GRC) and associated Gordon
Research Seminar (GRS) will bring together diverse researchers studying the mechanisms that protect the
genome against DNA damage, and the implications of these mechanisms in human diseases such as cancer.
In addition, the conference will promote discussions on how to target defects of the DNA damage response in
cancer therapy, and how to gain a better understanding of tumor evolution and therapeutic responses through
genomic approaches. The objectives are: 1) To expose researchers at all levels (faculty, researchers from
industry, postdoctoral fellows, and graduate students) to new frontiers of this rapidly progressing research field.
2) To provide opportunities for young scientists to network and practice presenting their research. 3) To generate
an atmosphere of inclusion and rigor that encourages the exchange of scientific ideas that may foster
collaborations or spur new innovation.4) To provide formal and informal career development opportunities. We
will achieve these objectives by assembling diverse speakers and poster presenters. 40% of the invited speakers
in the GRC are women and we expect approximately 45% of the GRS speakers be female trainees. This
GRC/GRS is notable compared to meetings on similar topics for the amount of unpublished research that is
presented, as well as the extensive informal discussion time during sessions, meals, and free time.

## Key facts

- **NIH application ID:** 10130900
- **Project number:** 1R13CA256897-01
- **Recipient organization:** GORDON RESEARCH CONFERENCES
- **Principal Investigator:** Lee Zou
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $6,000
- **Award type:** 1
- **Project period:** 2021-07-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10130900

## Citation

> US National Institutes of Health, RePORTER application 10130900, 2021 Mammalian DNA Repair Gordon Research Conference and Seminar (1R13CA256897-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10130900. Licensed CC0.

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