# Core B - Bone Biology Core

> **NIH NIH P01** · AUGUSTA UNIVERSITY · 2021 · $286,474

## Abstract

The purpose of the Bone Biology Core (Core B) is to provide a standardized set of bone assay services that
will facilitate completion of the broader goals and objections of the Program Project goals and specific aims.
The objective of this Program Project application is to understand how age-associated changes in the
epigenetic regulation of stem cells in bone can be modified by nutrient-related factors. Each of the four
projects investigates different aspects of these epigenetic- and nutrient-related signals, yet all will employ
similar techniques and animal models. The Bone Biology Core will provide each investigator with standard
assay services in the areas of bone histology and histomorphometry, imaging, densitometry, biomechanics,
and serum biochemistry. Dr. Mark Hamrick will be the core director. He is a bone biologist with experience and
expertise in the areas of bone histomorphometry, densitometry, and biomechanics with particular emphasis on
the use of animal models in bone metabolism research. He will be responsible for overseeing all
administrative issues related to the Core B facilities, as well as supervising the collection, preparation, and
distribution of bone specimens. The Core will serve as the major center for data collection related to bone
metabolism, and as such represents a key component linking the individual projects. Moreover, the Core
seeks to develop new technologies in support of future research activities related to the objectives of the
Program Project grant.

## Key facts

- **NIH application ID:** 10131723
- **Project number:** 5P01AG036675-10
- **Recipient organization:** AUGUSTA UNIVERSITY
- **Principal Investigator:** Mark W Hamrick
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $286,474
- **Award type:** 5
- **Project period:** 2011-05-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10131723

## Citation

> US National Institutes of Health, RePORTER application 10131723, Core B - Bone Biology Core (5P01AG036675-10). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10131723. Licensed CC0.

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