# Administration Core

> **NIH NIH P42** · UNIVERSITY OF KENTUCKY · 2021 · $177,006

## Abstract

PROJECT SUMMARY
The University of Kentucky Superfund Research Center (UK-SRC) will focus on a prevention and intervention
paradigm with an overarching goal to promote healthy lifestyles (i.e., healthful nutrition and increased physical
activity) to reduce disease risks associated with exposure to a subclass of persistent halogenated chemicals
(e.g. PCBs, TCE, and PFAS). Our biomedical research will be coupled with environmental science/engineering
research that uses novel sensing, remediation, and fate and transport science to prevent or reduce exposure
risks in the environment. Our biomedical research is integrated around a full life-span perspective and a
paradigm that uses animal studies to identify possible hypotheses that can be tested against existing human
databases to further identify potential intervention strategies. Our environmental science research is integrated
around a project cross-talk that uses fate and transport science to help inform technology development using
novel material science designed to reduce exposure to organic pollutants and that can then be deployed in
field applications. Both biomedical and environmental science projects are crosslinked around a common set of
pollutants and the use of animal models to test the toxicity of these pollutants and different remediation by-
products. To provide an optimal support environment and the requisite infrastructure to accomplish the
Center’s goal, we propose four specific aims for our Administrative Core (ADMC): 1) activities management
and integration, 2) bi-directional communication strategies, 3) partnerships and technology transfer, and 4)
evaluation and management processes. Management and integration functions are facilitated by monthly
Center meetings, and ADMC leadership and trainee interns are drawn from the individual research projects. Bi-
directional communication with other SRP centers and agency scientists and research translation to other
stakeholders are now fully integrated within the ADMC and overseen by a dedicated research translation
coordinator with support from a communications director. The ADMC effectively facilities investigator-initiated
research translation and technology transfer functions by leveraging a new integrated Data Management and
Analysis Core along with multidirectional internal (e.g. NIH funded UK Center for Clinical and Translational
Science (CCTS) WHY program, UK P30 pilot grants, Kentucky Water Institute) and external (e.g. EPA,
ADSTR, Kentucky Cabinet for Energy and the Environment (KYEEC), ARCADIS Consultants, individual water
utilities) partnerships. Evaluation and management processes are overseen by the ADMC director as assisted
by the program administer. The focus of the ADMC on the establishment and maintenance of a continuous
improvement development processes, along with internal and external relationships, positions the UK-SRC to
contribute not only important scientific findings but also to the collaborative processes and i...

## Key facts

- **NIH application ID:** 10133654
- **Project number:** 5P42ES007380-23
- **Recipient organization:** UNIVERSITY OF KENTUCKY
- **Principal Investigator:** BERNHARD HENNIG
- **Activity code:** P42 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $177,006
- **Award type:** 5
- **Project period:** 1997-04-07 → 2025-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10133654

## Citation

> US National Institutes of Health, RePORTER application 10133654, Administration Core (5P42ES007380-23). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10133654. Licensed CC0.

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