# Training in Neurotherapuetics and Development for Academic Scientists

> **NIH NIH R25** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2021 · $264,890

## Abstract

Project Summary/Abstract
 This project will develop and implement a training program in neurotherapeutics discovery and
development for faculty members and advanced postdoctoral fellows, centered around a 3½-day short course
that will provide the trainees with the various knowledge elements required to discover and advance a
neurotherapeutic agent to IND. Following the short course, the training program will continue for a two-year
period in which students will have individualized mentoring and assessment. The training, which is designed
to be applicable to diverse diseases of the nervous system, will equip students with a broad understanding
of the various component steps in the neurotherapeutics drug discovery and development process.
Students will learn how to identify a good drug discovery target; how to construct an assay; the elements of
medicinal chemistry; how to conduct animal efficacy testing; the principles of ADME studies, safety testing,
and formulation; the principles of experimental medicine and biomarkers; the steps required to prepare an
IND document and the principles for interacting with the FDA; the principles of intellectual property as they
relate to neurotherapeutics discovery and development; and how to seek funding for academic drug
discovery research. They will also receive training in responsible conduct of research. Students will be
equipped with the skills to develop and coordinate an entire drug discovery and development effort, and to
work collaboratively with experts in each of the component areas. The training will combine didactic lectures
with active engagement activities in which the students will be challenged to utilize the lecture material to work
through their own drug discovery project plan with the guidance of the area experts. The 3½-day short course
(followed by two-years of mentorship and assessment) will be offered annually, a total of five times.

## Key facts

- **NIH application ID:** 10134444
- **Project number:** 5R25NS099170-05
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** MICHAEL A. ROGAWSKI
- **Activity code:** R25 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $264,890
- **Award type:** 5
- **Project period:** 2017-05-15 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10134444

## Citation

> US National Institutes of Health, RePORTER application 10134444, Training in Neurotherapuetics and Development for Academic Scientists (5R25NS099170-05). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10134444. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*