# Administrative Supplement to Methods and Strategies for Chemical Synthesis

> **NIH NIH R35** · TRUSTEES OF INDIANA UNIVERSITY · 2020 · $53,203

## Abstract

Abstract for Supplement:
A key aspect of the ongoing research supported by the parent award is the synthesis of ladderane isostere
building blocks to be used in drug discovery. Critical to advancement of these studies is the large-scale
synthesis of these building blocks, which require multiple photochemical reactions. Due to unforeseen
challenges with scale up of these reactions, which are currently run in batch, we need to implement flow
processes. We are requesting funds to purchase a Vapourtec flow photochemistry system. This system will
allows for use of many different wavelengths of light, pressures and temperatures to easily scale up many
different photochemical reactions.

## Key facts

- **NIH application ID:** 10135249
- **Project number:** 3R35GM131755-02S1
- **Recipient organization:** TRUSTEES OF INDIANA UNIVERSITY
- **Principal Investigator:** Michael Kevin Brown
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $53,203
- **Award type:** 3
- **Project period:** 2019-04-01 → 2024-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10135249

## Citation

> US National Institutes of Health, RePORTER application 10135249, Administrative Supplement to Methods and Strategies for Chemical Synthesis (3R35GM131755-02S1). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10135249. Licensed CC0.

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