Project Summary/Abstract A clinical biochemistry analyzer is an essential piece of equipment for clinical pathology laboratories that assesses the function and response to injury of key organs such as liver and kidney. Many food contaminants/misformulations, toxins, microbial agents, cancer and other conditions affect these organs and can trigger biochemical changes measured by the biochemistry analyzer. The Oregon Veterinary Diagnostic laboratory (OVDL) has an AU480 biochemistry analyzer that is now 10 years old and lived its functional life expectancy, and therefore needs to be replaced. Our laboratory cannot function for a single day without a biochemistry analyzer. The OVDL receives a widely varied diagnostic caseload from domestic animals as well as wildlife, aquatic and marine species of the Pacific Northwest. The OVDL services are vital to a variety of clients and to public health, both of which are key to Vet LIRN’s mission. A biochemistry analyzer is necessary for the OVDL to be fully operational for Vet LIRN projects and investigations.