# Rapid Autopsy

> **NIH NIH P30** · JOHNS HOPKINS UNIVERSITY · 2021 · $178,637

## Abstract

ABSTRACT 
Postmortem examinations of patients, where the procedure commences shortly after death (rapid autopsies), 
are becoming an important scientific engine for understanding mechanisms of disease progression and drug 
resistance, especially in this era of personalized medicine and immunotherapy. Recently, the Department of 
Pathology and the Sidney Kimmel Comprehensive Cancer Center (SKCCC) recruited a new Director of 
Autopsy with a strong interest in rapid autopsy. The new Director started the Johns Hopkins Legacy Gift Rapid 
Autopsy Program, and it recently became an SKCCC Rapid Autopsy Program (RAP) Core. RAP Core 
members will: 
1) Perform rapid autopsies on cancer patients for studies related to therapeutic resistance mechanisms, 
immune evasion and correlation of molecular markers with clinical trial outcomes. 
2) Provide expert consultation and quality control/assurance in interpretation of autopsy histopathology 
samples, including fresh frozen tissues. 
3) Aid SKCCC and other investigators by providing administrative, technical and logistical support for 
performing rapid autopsies on patients with all tumor types. 
4) Expand and maintain a biorepository of fresh frozen tissues, FFPE tissues and fluid specimens from rapid 
autopsy cases, with full pathology and clinical annotations that can be accessed by qualified SKCCC 
investigators. 
5) Carry out molecular pathology-based biospecimen science studies to aid in the development and extension 
of best practices for tissue procurement, derivative specimen handling and sample storage. The Core utilizes 
the state-of-the-art Johns Hopkins Hospital postmortem facility. 
SKCCC-Managed Core 
Current Grant Year Reporting Period: Jan. 1, 2015, to Dec. 31, 2015

## Key facts

- **NIH application ID:** 10135894
- **Project number:** 5P30CA006973-58
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** EDWARD W. GABRIELSON
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $178,637
- **Award type:** 5
- **Project period:** 1997-05-07 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10135894

## Citation

> US National Institutes of Health, RePORTER application 10135894, Rapid Autopsy (5P30CA006973-58). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10135894. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*