# Viral Vector Core

> **NIH NIH P30** · UNIVERSITY OF PENNSYLVANIA · 2021 · $28,011

## Abstract

The Viral Vector Core is a critical resource for Diabetes Research Center (DRC) members interested in the use
of viral vectors for gene therapy and basic research applications. The Vector core provides adenoviral vectors,
adeno-associated viral vectors (AAV) and lentiviral vectors and offers a full range of services including cloning,
DNA amplification and characterization, vector design, and consultation. The Core is located within one of the
premier gene therapy research laboratories in the country and specializes in the production and distribution of
novel AAV serotype vectors. The objectives of the DRC Vector Core are as follows: Using state-of-the-art
facilities and dedicated professional staff, the Core will: (1) provide DRC Center members with access to high
quality vector technologies for basic research and preclinical studies; (2) work with DRC executive committee
members to develop vectors specifically for use by DRC members; (3) transition newly created vectors with
superior transduction profiles developed in Penn laboratories to the Core for validation and distribution to DRC
members and (4) provide consultation to DRC members for vector construction and experimental design. The
overall objective of the DRC Vector Core is to serve investigators at Penn and the surrounding scientific
community (e.g. Jefferson and Temple Universities) and aid in the advancement of diabetes-related research.

## Key facts

- **NIH application ID:** 10137230
- **Project number:** 5P30DK019525-45
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** JULIE JOHNSTON
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $28,011
- **Award type:** 5
- **Project period:** 1997-03-01 → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10137230

## Citation

> US National Institutes of Health, RePORTER application 10137230, Viral Vector Core (5P30DK019525-45). Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/grant/nih/10137230. Licensed CC0.

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