# Chem Science Facility Core

> **NIH NIH P30** · TEXAS A&M UNIVERSITY · 2021 · $169,150

## Abstract

Chem Science Facility Core ABSTRACT
The proposed Texas A&M Center for Environmental Health Research (TiCER) is focused on “Enhancing
Public Health by Identifying, Understanding and Reducing Adverse Environmental Health Risks.” Towards this
goal, the Chem Science Facility Core (CSFC) will provide Center investigators access to state-of-the-art
analytical and characterization tools for quantifying various exposure agents in the environment as well as
measuring biological markers of the effects of exposure from experimental model systems. The ability to measure
the levels of specific agents in the environment and detect biomarkers or signatures of downstream biological
effects in experimental models will enable Center investigators to develop dose-response studies for specific
agents, model the biological response as a result of exposure, and/or accurately predict the potential risk of
target populations to specific exposures. The CSFC will comprise three complementary components that
together will provide Center investigators with a continuum of analytical capabilities for comprehensively
characterizing the response to environmental exposures and contaminants. The chemical exposure science
component will provide state-of-the-art facilities for detection and quantitative analysis of potential environmental
toxicants in complex mixtures using gas and liquid chromatography-based mass spectrometry systems
(GC/MS/MS and LC/MS/MS). The genomics and microbiome component will provide molecular technologies
required for characterizing changes in genomic and transcriptomic signatures in tissues, single cells, and the
microbiota arising from environmental exposures. The metabolomics component will provide resources for
characterizing small molecule responses to environmental contaminants using LC/MS/MS and GC/MS/MS
platforms for both discovery and quantitation of biomarkers. While these foundational components already exist
as multi-user core facilities at Texas A&M, the CSFC is a new entity that will provide a mechanism for integrating
the diverse readouts and measurements across scales and with assistance of a data management specialist
from the Data Science Facility Core. Thus, the CSFC will not only leverage existing infrastructure at Texas A&M
but also provide novel capabilities and services to Center investigators under a single unified umbrella that would
otherwise be difficult to access. Integrating under a single thematic umbrella will also ensure that Center
investigators have access to the expertise and resources to investigate multiple facets of the response to
environmental contaminants across the exposure-response spectrum in a coordinated manner.
!

## Key facts

- **NIH application ID:** 10137243
- **Project number:** 5P30ES029067-03
- **Recipient organization:** TEXAS A&M UNIVERSITY
- **Principal Investigator:** ARUL JAYARAMAN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $169,150
- **Award type:** 5
- **Project period:** 2019-05-01 → 2024-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10137243

## Citation

> US National Institutes of Health, RePORTER application 10137243, Chem Science Facility Core (5P30ES029067-03). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10137243. Licensed CC0.

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