# Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Marketsand Drug Tourism

> **NIH NIH R01** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2020 · $153,045

## Abstract

To respond to the burgeoning SARSCoV-2 epidemic, we propose to leverage the infrastructure
of a new binational cohort of 600 people who inject drugs (PWID), as well as additional UCSD
investigators who have expertise in analysis of social networks, microbiome, and genetic
sequencing data to address the proposed aims:
Aim 1. To determine the prevalence and correlates of subclinical and symptomatic SARSCoV-2
infection among PWID within the SD/TJ border region.
Aim 2. To determine the prevalence and correlates of SARSCoV-2 shedding in nasal secretions
and fecal specimens among PWID.
Aim 3. To determine network features associated with cross-border transmission of subclinical
SARSCoV-2 infection among PWID.
Aim 4: To use molecular epidemiology to determine the global migration of SARSCoV-2 between
PWID in San Diego and Tijuana and factors associated with local and global dispersal.
We will use social network surveys, microbiome analysis and full length SARSCoV-2 sequencing
to characterize PWIDs’ social network determinants of SARSCoV-2 infection, the influence of the
microbiome on shedding, and the viral genetic migrations within SD, TJ and beyond. Accurate
estimates of subclinical infection of SARSCoV-2 and its risk factors are needed to inform
prevention, treatment, and public policy, especially in a cross-border context where border
closures have already been implemented as a costly measure to curb transmission.

## Key facts

- **NIH application ID:** 10138453
- **Project number:** 3R01DA049644-01A1S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** STEFFANIE A. STRATHDEE
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $153,045
- **Award type:** 3
- **Project period:** 2020-04-01 → 2025-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10138453

## Citation

> US National Institutes of Health, RePORTER application 10138453, Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Marketsand Drug Tourism (3R01DA049644-01A1S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10138453. Licensed CC0.

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