# UltraFISH+ for Single-cell Spatial Cell Type Analysis

> **NIH NIH R43** · DAVINCI BIO, INC. · 2021 · $300,000

## Abstract

SBIR Abstract
 Single cell biology is a multi-disciplinary study to investigate how large number of single
cells interact with each other as a complex system. In the Cell Atlas Era, identifying cell types
with high spatial resolution and accuracy is essential to decipher tissue heterogeneity and
understand the biological systems profoundly, and ultimately promote the development of next
generation clinical diagnostics and personalized medicine. However, existing technologies for
spatial cell type analysis have various technical limitations and can’t quantify tissue
heterogeneity at single cell level accurately and efficiently. UltraFISH+ is aiming to overcome
the limitations of existing single cell analysis technologies and become the best tool for spatial
cell type analysis. With the successful development of UltraFISH+, tissue heterogeneity will be
quantified accurately, efficiently and cost-effectively.

## Key facts

- **NIH application ID:** 10140219
- **Project number:** 1R43GM140605-01
- **Recipient organization:** DAVINCI BIO, INC.
- **Principal Investigator:** Wei Zhang
- **Activity code:** R43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $300,000
- **Award type:** 1
- **Project period:** 2021-05-15 → 2023-05-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10140219

## Citation

> US National Institutes of Health, RePORTER application 10140219, UltraFISH+ for Single-cell Spatial Cell Type Analysis (1R43GM140605-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10140219. Licensed CC0.

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