# Integrative  Technologies Support Core

> **NIH NIH P30** · UNIVERSITY OF CINCINNATI · 2021 · $219,682

## Abstract

PROJECT SUMMARY 
The mission of the Center for Environmental Genetics (CEG) is to study gene-environment (GxE) interactions, 
in response to chronic and/or acute exposure(s) to environmental agents across human lifespan, and their 
ensuing impact on the development of human disease and disability, with the ultimate aim of improving individual 
and population health. To accomplish this mission, our research requires high-end, cutting-edge technologies in 
environmental health sciences (EHS). The purpose of the CEG Integrative Technologies Support (ITS) Core is 
to furnish CEG members with the latest technologies in a manner that enhances research output, increases cost 
effectiveness, and maximizes the impacts of Center research. The ITS uses a model of providing direct subsidies 
for members to use leading-edge technologies in existing core facilities. The Core is structured to have maximum 
flexibility to change and adapt to new needs in EHS research as well as further technological advances. The 
inclusion of existing facilities in the ITS Core is based on usage, quality of services, technological 
novelty/investigative power, and services, in line with the vision of the CEG to integrate fundamental, 
translational, and clinical EHS research for the improvement of human health through cleaner environments. 
Facilities can be added or removed based on the aforementioned criteria. Aim 1 is to make state-of-the art 
specialized services available and affordable to Center members through subsidies and expert consultation. The 
components of the ITS Core are comprised of selected established facilities. CEG members can request 
matching funds for the use of these services as well as for methods development. Aim 2 is to ensure high-quality 
innovative technological support for members through the annual evaluation of usage, customer satisfaction of 
service, and the “right” composition of the ITS Core. The demand for a specific facility service changes based 
on the needs of the investigators or the exceptionality of the new technology. To remain nimble and up to date, 
components of the ITS Core will be evaluated annually by an evaluation committee. Aim 3 is to promote 
awareness of new technologies among current CEG investigators and assist in the recruitment of new members 
to the Center. The ITS Core will sponsor workshops and seminars on the technologies/services and educate 
and inform users on how these modern technologies can enhance research. The ITS Core is designed to be a 
nimble, fast, and fair system of subsidized usage of the latest technologies. It also seeks to encourage 
established facilities to develop new technologies meeting the needs of CEG members. The currently provided 
services include next-generation sequencing for research in genomics and epigenomics, proteomics, 
genotyping, in vivo genome editing, and flow cytometry. New technologies in development include single-cell 
genomics, and mitochondriomics. The ITS Core stimul...

## Key facts

- **NIH application ID:** 10142476
- **Project number:** 5P30ES006096-29
- **Recipient organization:** UNIVERSITY OF CINCINNATI
- **Principal Investigator:** YING XIA
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $219,682
- **Award type:** 5
- **Project period:** 2020-04-01 → 2023-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10142476

## Citation

> US National Institutes of Health, RePORTER application 10142476, Integrative  Technologies Support Core (5P30ES006096-29). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10142476. Licensed CC0.

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