PROJECT SUMMARY This proposal is for support of partial registration costs for speakers, discussion chairs and selected attendees of the 2021 `Dendrites: Molecules, Structure and Function' Gordon Research Conference and associated Graduate Research Seminar. This Gordon Research Conference reflects the growing understanding that dendrites play a central role in neuronal computation. Thousands of synaptic inputs arrive at different locations along a neuron's dendrites and that the subsequent integrative process ultimately determines that neuron's output. Recent advances in molecular, electrophysiological, and imaging techniques have led to a new picture of dendrites, and a deeper understanding of their computational role. Many complex mechanisms shape dendritic structure, function, and connectivity. Further, dendrites can undergo plastic changes in structure and function during development and learning, but also during neurodevelopmental and neurodegenerative disease. Computational and theoretical approaches have further refined our views of dendrites and their unique role in brain function. This Gordon Research Conference will bring together researchers whose latest findings help clarify how the molecular and electrophysiological properties of dendrites enable them to perform complex computations important for sensory-motor processing and higher cognitive function. The conference will be of interest to researchers and students in neuroscience, as well as to anyone interested in normal and abnormal brain function. There are three specific aims or goals associated with this conference: Specific Aim 1: To provide a forum for the presentation and discussion of state-of-the-art research on dendrite structure and function in the healthy brain and in disease. Specific Aim 2: To provide opportunities for engagement between investigators at all career stages, from diverse backgrounds, a range of educational and research institutions, and from disparate geographic locations. Specific Aim 3: To attract early career scientists to the dendrites field and mentor their development. A Graduate Research Seminar (GRS) held prior to the main meeting will allow young investigators to interact with their peers and present their work in a relaxed environment. The GRS will also feature a professional development panel discussing careers in and out of academia.