# Biomedical Research Support Shared Resource

> **NIH NIH P30** · WISTAR INSTITUTE · 2021 · $171,497

## Abstract

PROJECT SUMMARY – BIOMEDICAL RESEARCH SUPPORT SHARED RESOURCE
New Cancer Center Support Grant Shared Resource
The Biomedical Research Support Shared Resource (BRSSR) enables Cancer Center members to perform
human subject research in the context of partnerships between Wistar investigators and clinical care providers.
Introduced as a developmental core at the 2013 Cancer Center Support Grant (CCSG) renewal, the BRSSR
has been launched as a full-service Cancer Center Shared Resource during the last CCSG budget cycle. By
providing a centralized resource for human subject-based research at Wistar, the BRSSR makes available to
Cancer Center investigators a comprehensive menu of services to (i) coordinate the procurement of human
subject-derived biospecimens from clinical partners, volunteers (phlebotomy service) or commercial partners; (ii)
provide expertise in fulfilling research compliance with ethical and regulatory mandates; (iii) assist investigators
to ensure that biospecimen and data collection is conducted in compliance with Good Clinical Practice (GCP),
regulatory mandates (e.g. 21 CFR Part 11, HIPAA etc.) and contractual obligations; (iv) provide access to tissue
processing and advanced histotechnology techniques for specimens analysis; and (v) provide low-cost,
customized solutions for centralized data storage and management that ensure the consistency, completeness
and quality of the data received from clinical providers. Our collaborative partnership with the Helen F. Graham
Cancer Center (HFGCC) at Christiana Care Health System (CCHS), a member Institution of the National
Community Cancer Center Program (NCCCP), provides Wistar Cancer Center members with access to fresh
biospecimens, including fine-needle aspirate, biopsies, surgical resections, and biological fluids from cancer
patients, instrumental to fulfill the mission of the Cancer Center in translational and patient-focused cancer
research. Substantial institutional investments have been made to develop and validate an electronic data
management platform, CDETweb® Toolbox, to manage human subject data in the BRSSR. As fully deployed,
the CDETweb® platform is customizable to meet specific data collection and sample tracking needs, supporting
multiple data entry modes (e.g. keying and direct uploads), randomization, asymmetrical visit schedules,
screening and entry criteria gatekeeping, and other custom-defined requirements. BRSSR services also support
a phlebotomy service (protocol management, donor management, testing, etc.) and access to tissue microarray
services (array design and customization, ordering and tracking). As a result, the BRSSR provides a robust
infrastructure to support mechanistic, patient-oriented research by managing all aspects of procurement of
human subject-derived biospecimens.

## Key facts

- **NIH application ID:** 10145609
- **Project number:** 5P30CA010815-52
- **Recipient organization:** WISTAR INSTITUTE
- **Principal Investigator:** Luis J Montaner
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $171,497
- **Award type:** 5
- **Project period:** 1997-04-01 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10145609

## Citation

> US National Institutes of Health, RePORTER application 10145609, Biomedical Research Support Shared Resource (5P30CA010815-52). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10145609. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*