# Dynamics of Contemporary Genomic Evolution in Replicate Threespine Stickleback Populations

> **NIH NIH R01** · STATE UNIVERSITY NEW YORK STONY BROOK · 2020 · $6,699

## Abstract

Project Summary
The NIH funded parent award uses genomics of threespine stickleback to address questions about the
mechanism of rapid adaptation from standing genetic variation. It focuses primarily on anadromous threespine
stickleback in Alaska that have recently been transplanted into freshwater environments and exhibited major
phenotypic change. An important finding from the parent grant thus far has been that the starting haplotype
structure on which freshwater-adaptive alleles lie in the anadromous population is key to how rapidly alleles will
evolve in a new freshwater environment. The proposed undergraduate summer research project will examine
65 whole genomes from three anadromous Stickleback populations from Alaska and the Pacific Northwest in
order to elucidate patterns of haplotype sharing across marine environments. The candidate will learn how to
perform the bioinformatic processing necessary to generate high coverage whole genomes that can then be
analysed using various downstream data manipulation, visualization and population genetics methods. This
proposed summer research is closely associated with Aim 1 of the parent NIH grant and will provide the
candidate with the opportunity to develop technical skills in accessing and using remote computer clusters,
processing 2nd generation sequencing data, asking biologically relevant questions and interpreting and
visualizing data. In addition, the candidate will also obtain exposure to being in a lab group, interacting with
students and staff at various levels and participating in lab meetings and a journal club. The candidate will also
present their work at an undergraduate research symposium hosted by Stony Brook University in 2021. Due to
the COVID-19-related restrictions in the state of New York, this project will be carried out remotely.

## Key facts

- **NIH application ID:** 10145871
- **Project number:** 3R01GM124330-03S1
- **Recipient organization:** STATE UNIVERSITY NEW YORK STONY BROOK
- **Principal Investigator:** Krishna R Veeramah
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $6,699
- **Award type:** 3
- **Project period:** 2017-09-15 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10145871

## Citation

> US National Institutes of Health, RePORTER application 10145871, Dynamics of Contemporary Genomic Evolution in Replicate Threespine Stickleback Populations (3R01GM124330-03S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10145871. Licensed CC0.

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