# CEGS Admin Supplement for Years 3-5

> **NIH NIH RM1** · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2020 · $499,698

## Abstract

Title: Center for Synthetic Regulatory Genomics
Abstract
The Center for Synthetic Regulatory Genomics (SyRGe) is tasked with development and
application of revolutionary technology for making dramatic, coordinated changes to
extensive gene loci, which will enable broad investigation of the function of regulatory
sequences and foster translational applications to biotechnology, personalized medicine
and gene therapy. Specifically, we will increase the scope/productivity of the Center from
3 loci per year to 4 (minimum) or 5 loci per year in years 3, 4, and 5. Additionally the
Center will further the development of a new big DNA integration technique called
mSwAP-In which his capable of iteratively integrating large DNA segments in stem cells,
by determining the length limit of DNA that can be introduced at each step.

## Key facts

- **NIH application ID:** 10146013
- **Project number:** 3RM1HG009491-03S1
- **Recipient organization:** NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- **Principal Investigator:** Jef D BOEKE
- **Activity code:** RM1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $499,698
- **Award type:** 3
- **Project period:** 2020-04-16 → 2023-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10146013

## Citation

> US National Institutes of Health, RePORTER application 10146013, CEGS Admin Supplement for Years 3-5 (3RM1HG009491-03S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10146013. Licensed CC0.

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