# Chasing Covid Cohort

> **NIH NIH UH3** · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · 2020 · $2,653,115

## Abstract

Abstract
 Immediate characterization of the effects of non-pharmaceutical interventions (NPIs) on community
SARS/COV2 spread will be essential to safely re-opening the U.S. economy. We propose integration of rapid
serologic assessment and extension of follow-up in an existing national cohort study of SARS/COV2, the
CHASING COVID Cohort (C3) study. Launched on March 28th, 2020, we have already enrolled >4,700 adult
participants from all 50 U.S. states and Puerto Rico into longitudinal follow-up (Figure), providing the opportunity
for rapid investigation of the effect of different NPIs on SARS/COV2 spread in the United States. With this new
application for funding, we seek to expand on this work by adding rapid serologic testing and extending
follow-up to address the following specific aims: 1. Estimate the cumulative incidence of SARS/COV2, and
evaluate impact of different NPIs on the cumulative incidence of SARS/COV2 infection, COVID (disease), and
COVID deaths; 2. Estimate the proportion of persons with serologic evidence of SARS/COV2 infection who were
asymptomatic or had only mild symptoms; 3. Assess whether SARS/COV2 antibodies are protective against
subsequent COVID disease. We will conduct in-depth interviews with participants to help contextualize and
interpret key findings. To help increase the scientific impact of this project, we will post public use datasets on
GitHub, along with software tools. By deploying specimen collection now, the rapid knowledge gained by
addressing the above aims will help inform policy and implementation and relaxing of NPIs, as well as
mathematical models, in the US and around the world.

## Key facts

- **NIH application ID:** 10146744
- **Project number:** 3UH3AI133675-04S1
- **Recipient organization:** GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY
- **Principal Investigator:** Christian Grov
- **Activity code:** UH3 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,653,115
- **Award type:** 3
- **Project period:** 2020-08-01 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10146744

## Citation

> US National Institutes of Health, RePORTER application 10146744, Chasing Covid Cohort (3UH3AI133675-04S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10146744. Licensed CC0.

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