# DANA; A Tool to Detect Cognitive Changes in Pre-clinical and MCI Patients (Admin Supplement)

> **NIH NIH R44** · ANTHROTRONIX, INC. · 2020 · $484,753

## Abstract

Project Summary/Abstract
The goals of this proposed project are to develop the DANA app into a tool that can be
easily used remotely by COVID-19 patients after discharge from an Intensive Care Unit
(ICU) and to provide clinicians with meaningful data on the immediate and long term
effects of COVID-19 on a patient’s cognitive function. DANA will also help clinicians
optimize neurocognitive rehabilitation. DANA is an FDA-cleared neurocognitive
assessment tool that has been shown to be a valid and reliable method for screening
cognitive functioning and tracking changes in cognitive functioning over time.
Importantly, DANA can provide results virtually through a HIPAA-compliant portal, which
will protect the clinician and others from exposure to the patient.
The specific aims of the proposal are: (1) technical modifications and support of DANA
for in-home self-administration and remote monitoring of COVID-19 patients, and (2)
deploy and show efficacious use of DANA with recovering COVID-19 patients. These will
build on the specific aims of the current Phase II SBIR, which includes the same
longitudinal surveillance for participants either at-risk for Alzheimer’s or diagnosed with
Mild Cognitive Impairment (MCI).
Three control populations, composed of (1) hospitalized COVID-19 patients who do not
require ICU admission, (2) post-discharge ICU patients without COVID-19, and (3)
healthy participants from the Alzheimer’s Disease Center Registry. All participants will be
given DANA immediately before leaving the hospital to determine a baseline, then they
will administer the DANA tests to themselves while they convalesce in isolation.
Technical changes specific to the needs of COVID-19 patients will be made to the DANA
software in order to make DANA easier to use at home and provide optimal data to the
clinician.

## Key facts

- **NIH application ID:** 10147564
- **Project number:** 3R44AG063635-02S1
- **Recipient organization:** ANTHROTRONIX, INC.
- **Principal Investigator:** CORINNA E LATHAN
- **Activity code:** R44 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $484,753
- **Award type:** 3
- **Project period:** 2019-07-01 → 2020-09-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10147564

## Citation

> US National Institutes of Health, RePORTER application 10147564, DANA; A Tool to Detect Cognitive Changes in Pre-clinical and MCI Patients (Admin Supplement) (3R44AG063635-02S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10147564. Licensed CC0.

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