# Admin Supp to: The Health ePeople Resource for Mobilized Research

> **NIH NIH U2C** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2020 · $782,723

## Abstract

OVERALL— PROJECT SUMMARY/ABSTRACT
We seek to create the Health ePeople Resource, a nimble, readily-accessible, and reliable infrastructure to
conduct mHealth research. This effort will build on the current Health eHeart Study, an internet-based clinical
research platform that has enrolled more than 20,000 engaged participants from around the world. Although
initially developed to study cardiovascular disease, Health eHeart is in use by investigators from multiple fields,
and helps us jumpstart many of the objectives set out in the current RFA. We have successfully implemented a
user-friendly interface built to collect patient-reported outcomes, validated survey data, and integrations with
multiple sensors, devices, and apps; we have an IRB approved system using modular electronic consenting;
we have over 20,000 deeply involved participants interested in contributing to mHealth research; we have
developed ways for external investigators to utilize and enroll their own participants in a customizable fashion;
we have developed a study management portal (including a real-time dashboard and participant characteristic-
based filtering system) and a flexible messaging system that can be utilized by external investigators; we have
built a database and data management system constructed to adhere to the highest standards of privacy,
security, and reliability; and we have iterated and adapted the platform to take advantage of emerging
technology and cutting-edge methods. Building from these strengths, we are ready to fully leverage the
opportunities afforded by this award, transforming the Health eHeart Study into a general Health ePeople
Resource. The primary goal of Health ePeople will be to provide a resource that enables convenient and
efficient mHealth research. The Resource will help investigators collect mHealth data via integration with
sensors, devices, and apps, deliver online surveys, connect with external data sources including electronic
health records, and use novel methods for ascertaining and adjudicating clinical outcome events. The
Resource will support utilization of patients already enrolled in the Health ePeople Cohort or “co-enrollment”
(and data linkage) of participants recruited externally. We will utilize our experience engaging and consenting
more than 20,000 patients grow and expand a world-wide cohort of participants (the Health ePeople Cohort)
interested in contributing to mHealth research. The platform will support development and validation of apps,
including randomized controlled trials. This effort will leverage our experience working with foundations and
patient-advocacy groups as well as our position in PCORnet and the resultant collaborative relationships with
multiple large PCORI-funded Clinical Data Research Networks that can provide access to hundreds of millions
of patients and their electronic health records. We will develop the technology, procedures and governance to
support rapid access to the Health ePeople coho...

## Key facts

- **NIH application ID:** 10147565
- **Project number:** 3U2CEB021881-05S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** GREGORY M MARCUS
- **Activity code:** U2C (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $782,723
- **Award type:** 3
- **Project period:** 2020-07-07 → 2021-07-06

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10147565

## Citation

> US National Institutes of Health, RePORTER application 10147565, Admin Supp to: The Health ePeople Resource for Mobilized Research (3U2CEB021881-05S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10147565. Licensed CC0.

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