Step down of asthma biologics in real-world practice settings

NIH RePORTER · NIH · R21 · $21,370 · view on reporter.nih.gov ↗

Abstract

Our overall goal is to identify risk factors in people with asthma for being hospitalized for COVID-19. Our team is uniquely positioned to quickly analyze pre-existing data that includes risk factors likely to be relevant for people with asthma who are hospitalized for COVID-19. Our team has used a claims data set that includes 200+ million people residing in the US in multiple studies in people with asthma called OptumLabs Database Warehouse (OLDW). We hypothesize that there are behavior, health care delivery, and patient demographic factors associated with hospitalization for COVID-19 in people with asthma. To test this hypothesis, we will analyze pre-existing data from OLDW, testing the following independent variables: age, sex, race-ethnicity, smoking, comorbid chronic diseases, geographic region, rural/urban residence, access to provider care (traditional and telehealth), medication-filling behavior, and types of asthma medications filled.

Key facts

NIH application ID
10148448
Project number
3R21HL140287-02S1
Recipient
MAYO CLINIC ARIZONA
Principal Investigator
Matthew A Rank
Activity code
R21
Funding institute
NIH
Fiscal year
2020
Award amount
$21,370
Award type
3
Project period
2020-09-01 → 2021-08-31