# Laboratory Animal Shared Resource

> **NIH NIH P30** · ROSWELL PARK CANCER INSTITUTE CORP · 2021 · $275,153

## Abstract

The mission of the Laboratory Animal Shared Resource (LASR) is to promote the humane care and use of
laboratory animals in support of basic and translational research conducted at Roswell Park. The facilities and
veterinary program are both accredited by AAALAC International demonstrating the commitment to humane
and responsible animal research and dedication to good science. LASR is designed to offer the highest
standards of animal care, with an expert technical staff performing all aspects of daily health observations,
veterinary medical care, facility and equipment maintenance and surgical and technical services. The LASR
offers CCSG members a full spectrum of laboratory animal care and use services including barrier facilities
with fully automated environmental controls for the housing of research animal models. The LASR provides
veterinary medical care, animal health surveillance, diagnostic laboratory facilities, irradiation services,
research technical services and faculty training in support of more than 200 Institute Animal Care and Use
Committee-approved animal use protocols and specialized animal husbandry with trained staff that performs
all husbandry manipulations during cage changing inside Bio-Safety cabinets for maintenance of a pathogen-
free environment of animals held in micro isolation (MI) caging systems. The main site is a four-story ~50,000
net square feet (nsf) vivarium, which opened in 1998, located in the Medical Research Complex building. An
additional 9,000 nsf is available in the adjacent Cancer Cell Center building. The animal inventory fluctuates
between 39,000 to 42,000 animals housed in the facility. In the reporting period (2013-2017), the LASR served
a total of 129 Roswell users, of which 106 (82%) were CCSG members. LASR supports scientists that conduct
in vivo studies. To further the success of the research programs within the cancer center, the LASR is actively
involved in refinement of procedures that usually become new methods or innovations to accomplish the goals
of proposed animal studies. The Specific Aims of the LASR are: 1) To provide Roswell Park CCSG members
access to state-of-the-art facilities, specialized husbandry and veterinary services for the housing and care of
their laboratory animals used in research; 2) To propel the transition from basic and translational in vitro
research into clinical application and practice using in vivo animal models of cancer; 3) To provide intellectual
and technical support to assist basic and clinical investigators in all CCSG programs during experimental
design, execution of projects and manuscript and/or grant writing. The goal of the LASR is to support
biomedical research at the cancer center while maintaining the highest standards for the humane care and use
of the laboratory animals. LASR will continue to maintain the AAALAC International accreditation for assurance
of gold standards of animal care.

## Key facts

- **NIH application ID:** 10148657
- **Project number:** 5P30CA016056-44
- **Recipient organization:** ROSWELL PARK CANCER INSTITUTE CORP
- **Principal Investigator:** Sandra Sexton
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $275,153
- **Award type:** 5
- **Project period:** 1997-06-16 → 2024-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10148657

## Citation

> US National Institutes of Health, RePORTER application 10148657, Laboratory Animal Shared Resource (5P30CA016056-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10148657. Licensed CC0.

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