# Core-007

> **NIH NIH UL1** · UNIVERSITY OF COLORADO DENVER · 2021 · $308,795

## Abstract

The overall goal of our Early Life Exposures Program (ELEP) Optional Component is to enable investigators
in diverse disciplines and all career stages to train, participate, and excel in research focusing on human health
and diseases that have their origins at early stages of life. As a result, the ELEP will foster a new generation of
scientists trained in the complexities of translational research involving pregnant women and their offspring from
infancy through childhood and adolescence. The premise of our ELEP is that pre-emption of diseases and
prevention of their later life consequences will improve health and quality of life by reducing disease burden and
its devastating economic impact on individuals and society. Thus ELEP will align with the CTSA Lifespan Domain
Task Force through objectives focused on early life exposures. Within the CCTSI framework, the ELEP will
integrate a large number of existing and well-funded research programs in maternal-placental-fetal and pediatric
medicine, each with multiple investigators and trainees. The ELEP will support new multidisciplinary
collaborations among basic/pre-clinical, clinical, and translational scientists at the University of Colorado
Anschutz Medical Campus (CU-AMC) and in the CCTSI community. The ELEP will provide research and training
infrastructure to facilitate early life exposures research and longitudinal lifespan/life course research. The ELEP
will provide an innovative platform for prospective, observational and experimental approaches as a national
model for CTSA centers engaged in lifespan research in order to promote collaborations among CTSA hubs.
These goals will be achieved by the following Specific Aims: Aim 1: Expand and streamline our broad-based,
multidisciplinary organizational structure to promote Early Life Exposures clinical-translational research in the
CCTSI. Aim 2: Provide coordinated research support and development. Aim 3: Foster new education and
training opportunities in Early Life Exposures research. By implementing these aims over the next 5 years, we
will enhance the ability of our numerous outstanding scientists and team-based research programs, and attract
and train new investigators, in child-maternal health research to have a significant and sustained impact on
human health and development, with the ultimate goal of translating discoveries into interventional studies and
clinical trials very early in life with high potential to improve quality of life across the lifespan.

## Key facts

- **NIH application ID:** 10149437
- **Project number:** 5UL1TR002535-04
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** RONALD J. SOKOL
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $308,795
- **Award type:** 5
- **Project period:** 2018-05-01 → 2023-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10149437

## Citation

> US National Institutes of Health, RePORTER application 10149437, Core-007 (5UL1TR002535-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10149437. Licensed CC0.

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