# University of North Carolina - Chlamydia Vaccine Initiative (UNC-CVI)

> **NIH NIH U19** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2021 · $219,154

## Abstract

To advance the development of vaccines against major sexually-transmitted diseases, NIAID announced the
the U19 Sexually Transmitted Infections Cooperative Research Center (STI CRC) program. In response, the
University of North Carolina Chlamydia Vaccine Initiative (UNC-CVI) has assembled a group of seasoned
Chlamydia researchers, STI clinicians and vaccine development experts to address the development of a
vaccine to prevent the often-devastating health and reproductive consequences of Chlamydia infection in
women. UNC-CVI will be a large and multifaceted organization, encompassing cores, projects and
collaborators at multiple national and international sites. Establishing and maintaining the infrastructure to
ensure the smooth and efficient running of this enterprise will be the responsibility of the Administrative Core
A. Headed by Center PI Toni Darville MD and project PI Catherine O’Connell PhD, and backed by resources at
UNC Chapel Hill, one of the country’s leading research universities. Core A leadership will combine scientific
expertise with administrative experience to ensure the successful completion of the following specific aims: 1
– Administrative oversight, ensure that UNC-CVI scientists and staff work synergistically to accomplish the
short- and long-term goals of the Center’s research program, including management of finances, resources
and biospecimens; 2 – Communications oversight – provide a conduit for the disparate components of the
Center and NIH to share data and results, troubleshoot roadblocks, and disseminate information to the
scientific community and the public; 3 – Scientific oversight – monitoring milestones and deliverables, and
overseeing conflict resolution, reagent- and data sharing and intellectual property issues; 4 – Developmental
oversight, developing and administering the Development Research Program, to support the research and
careers of the next generation of STI vaccine researchers; 5 – Biostatistical support group, ensuring the Center
projects and DRP awardees have access to the cutting-edge statistical expertise essential for effective basic,
translational and clinical research.

## Key facts

- **NIH application ID:** 10149920
- **Project number:** 5U19AI144181-03
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** Toni Darville
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $219,154
- **Award type:** 5
- **Project period:** 2019-05-01 → 2024-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10149920

## Citation

> US National Institutes of Health, RePORTER application 10149920, University of North Carolina - Chlamydia Vaccine Initiative (UNC-CVI) (5U19AI144181-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10149920. Licensed CC0.

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