# Multidisciplinary research training in pulmonary diseases

> **NIH NIH T32** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2021 · $254,790

## Abstract

Abstract
This renewal for years 41-45 of the Program in “Multidisciplinary Training in Pulmonary Diseases” at The
University of North Carolina at Chapel Hill supports six postdoctoral trainees with M.D., M.D./Ph.D. or Ph.D.
degrees for research training in Respiratory Medicine, emphasizing a joint training program for Medicine and
Pediatric trainees. The Program provides multidisciplinary training in basic, translation and clinical research
within the pulmonary divisions of the Departments of Medicine and Pediatrics and our three Centers devoted to
understanding lung health and disease. The breadth of training provided by the Program is expanded by
faculty from 12 clinical (3) and basic science (9) departments in the Schools of Medicine and Public Health and
the College of Arts and Sciences. M.D. trainees will enter a 3-5 year clinical and research training experience
designed to provide them with skills required for a career in academic pulmonary medicine. Ph.D. trainees will
typically enter in the second year of their post-doctoral fellowship, and they will be well integrated into the
translational and clinical research components, as well as the basic science. Each trainee will have a scholarly
oversight committee that includes trainers from varying disciplines who will facilitate their scientific growth.
Each area of lung research offered by the Program is multidisciplinary in nature and emphasizes a knowledge
of the basic, translational, clinical and impact implications for each trainee's question, even though a trainee's
research focuses on one aspect. Areas of research include the genetic basis of airways diseases, particularly
cystic fibrosis, primary ciliary dyskinesia, and idiopathic bronchiectasis, cell and molecular biology of airway
epithelia in health and disease, inflammatory and innate immune responses during bacterial and viral infections,
endothelial cell biology and vascular permeability in infection and ARDS, outcomes research and clinical trials
in critical care, the control of airway inflammation, basic and translational proteomics of airways, the airway
microbiome in health and in cystic fibrosis and COPD, airway function and leukocyte kinetics in COPD,
comparative effectiveness research in COPD, the responses to injury by physical, chemical, and microbial
environmental agents, and clinical and basic studies in asthma. Novel programs that exemplify the multi-
disciplinary nature include the Virtual Lung Project, ARDS and Critical Care Research, and the COPD-Lung
Cancer Working Group, each of which require cross-disciplinary interactions amongst a very wide range of
expertise to accomplish their goals. Clinical studies will be integrated with basic observations using
translational physiologic, biochemical, molecular and genetic technologies and Omics approaches and will
provide training in state-of-the-art bioinformatics, database design, use and analyses, and statistical
interpretation. Emphasis is on mechanisms underlying ...

## Key facts

- **NIH application ID:** 10152664
- **Project number:** 5T32HL007106-45
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** Richard Charles Boucher
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $254,790
- **Award type:** 5
- **Project period:** 1975-07-01 → 2024-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10152664

## Citation

> US National Institutes of Health, RePORTER application 10152664, Multidisciplinary research training in pulmonary diseases (5T32HL007106-45). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10152664. Licensed CC0.

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