# Harmonized Diagnostic Assessment of Dementia (DAD) for Longitudinal Aging Study of India (LASI)-Genomic study

> **NIH NIH U01** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2020 · $360,284

## Abstract

Project Summary
The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is
the first and only nationally representative and publicly available dataset on late-life cognition and dementia in
India. It administers the Harmonized Cognitive Assessment Protocol (HCAP) that is designed to be
harmonized with ongoing longitudinal studies of aging around the world, including the Health and Retirement
Study (HRS) in the United States, and prior studies in India. This rich set of cognitive phenotypes and a variety
of other health and social environment phenotypes, as well as genotype data from whole genome sequencing,
give us a unique opportunity to identify the mutational spectrum underlying risk of dementia and AD in a
representative sample of India.
 In this application, we aim to monitor and investigate the impacts of Coronavirus Disease 2019 (COVID-19)
on the LASI-DAD households through phone surveys. The COVID-19 pandemic will fundamentally alter the
lives of individuals across the world, and India is not an exception. To gain insight into the health and economic
impacts of the pandemic, we propose to track the LASI-DAD households and conduct quarterly phone
interviews for 1-year. Through continuous monitoring, we will assess how individuals’ knowledge, attitudes,
and behaviors related to the disease change over time, as well as the health and economic impacts of the
pandemic. The collected data will be linked to the follow-up Wave 2 LASI-DAD for the estimation of their
impacts on cognitive changes and dementia incidence.

## Key facts

- **NIH application ID:** 10153290
- **Project number:** 3U01AG064948-02S1
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Sharon L Kardia
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $360,284
- **Award type:** 3
- **Project period:** 2019-09-15 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10153290

## Citation

> US National Institutes of Health, RePORTER application 10153290, Harmonized Diagnostic Assessment of Dementia (DAD) for Longitudinal Aging Study of India (LASI)-Genomic study (3U01AG064948-02S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10153290. Licensed CC0.

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