Project Summary Community-based participatory research builds partnerships between communities and researchers to engage in research design, decision making, data collection, and dissemination of health promotion initiatives. This community-based participatory research project proposal, submitted through an NIGMS administrative supplemental funding opportunity, is a pat1nership with collaboration. Specifically, beginning the fall of 2020, INBRE-supported researchers within the South Dakota Biomedical Research Infrastructure Network (SD BRIN) and researchers in the Nebraska IDeA-CTR will collaborate with a rural American Indian community. The researchers will assess health disparities, including obesity and Type II diabetes within youth from ages 5 to 18, and will both implement and evaluate cultural and physical activity interventions. This youth physical activity program is an attempt to prevent future health complications and achieve health equity, or as the American Indian culture would rather say: achieve a culture of equality, harmony, and whichozani-a healthy lifestyle. Through this collaboration, training in the experimental collection, data analysis, and interpretation of physical activity data will be provided from Dr. Knarr's research group to the undergraduate SD BRIN fellows. Impo11antly, the SD BRIN fellows will receive hands-on experience in the collection of physical activity data through successful execution of this project, as SD BRIN students will be responsible for the experimental setup and retrieval of activity- monitoring devices. This training is highly complementary to the research focus of Dr. Smith and her team, whose expertise centers on the implementation of activity and health promotion programs.