# Partnerships for Biomedical Research in Arkansas - Admin Supplement

> **NIH NIH P20** · UNIV OF ARKANSAS FOR MED SCIS · 2020 · $165,326

## Abstract

Abstract
Research experiences are widely recognized to benefit undergraduate students in a number of ways including
increased likelihood of: 1) graduating with a baccalaureate degree, 2) additional post-baccalaureate training in
either graduate school or professional school, and 3) a career in research. This administrative supplement is a
collaborative project between the Arkansas INBRE and the CTSA-funded UAMS Translational Research
Institute that will provide a team-based translational research experience that addresses a critical health care
issue to a cohort of Hendrix College undergraduate students. Students will participate in an ongoing study that
has as a major goal, determination of an optimal treatment strategy for mothers with opioid use disorder (OUD)
in order minimize the impact of neonatal opioid withdrawal syndrome (NOWS) on newborns. Buprenorphine
(an opioid prescribed to mothers with OUD) and norbuprenorphine (a metabolite of buprenorphine) will be
measured in blood samples obtained from maternal-infant pairs. The maternal and infant buprenorphine and
norbuprenorphine levels will be correlated with the need for NOWS treatment and clinical co-variates
determined including duration of hospitalization of infants following birth and post-hospitalization assessment
of NOWS using the Finnegan Neonatal Abstinence Scoring Tool. The students will work together in teams and
will receive foundational knowledge in basic analytical methodologies, participate in all aspects of the research
including drug and metabolite analysis, as well as measurement and analysis of clinical co-variates of NOWS.
The effectiveness of the research experience in impacting the students' perception of research and their
overall satisfaction of with the program will be assessed through a survey previously developed by the
Arkansas INBRE and used as part of its Summer Research Program for Undergraduates. In addition, the
participating students' post-baccalaureate training choices, career goals, and future employment will be
tracked in order to understand the value of the research experience.

## Key facts

- **NIH application ID:** 10154021
- **Project number:** 3P20GM103429-19S1
- **Recipient organization:** UNIV OF ARKANSAS FOR MED SCIS
- **Principal Investigator:** Lawrence E Cornett
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $165,326
- **Award type:** 3
- **Project period:** 2001-09-30 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10154021

## Citation

> US National Institutes of Health, RePORTER application 10154021, Partnerships for Biomedical Research in Arkansas - Admin Supplement (3P20GM103429-19S1). Retrieved via AI Analytics 2026-06-11 from https://api.ai-analytics.org/grant/nih/10154021. Licensed CC0.

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