# NA-ACCORD COVID-19 Supplment

> **NIH NIH U01** · JOHNS HOPKINS UNIVERSITY · 2020 · $152,652

## Abstract

ABSTRACT
The North American – AIDS Cohort Collaboration on Research and Design (NA-ACCORD), the Region 1
representative of the IeDEA network, aims to describe the HIV epidemic in the US and Canada and answer
questions important to the contemporary care and health of persons with HIV. We propose to leverage the
research infrastructure of the NA-ACCORD to support our infectious disease epidemiologists and clinical co-
investigators as they pivot to answer urgent COVID-19 questions in people with (PWH) and without (PWOH)
HIV among existing and new cohorts. By supporting a) 2 existing cohorts and the establishment of 3
longitudinal COVID-19 clinical cohorts curated from available electronic health record (EHR data), b) data
management and analytic expertise specific to the profound health impacts of infectious disease, c) a library of
COVID-19 data collection tools, and d) the sharing of EHR-based algorithms for COVID-19, we will accelerate
the answers to the following urgent COVID-19 questions: 1) Who is getting tested for SARS-Cov-2, what
proportion are positive, and what are predictors of a positive test? 2) What are risk factors for hospitalization
after testing positive for SARS-Cov-2? 3) Do angiotensin-converting enzymes (ACE) inhibitors or angiotensin II
type-I receptor blockers (ARBs) increase the risk of severe COVID-19 illness? 4) What is the impact of the
healthcare system’s adaptation to the surge of people becoming ill with COVID-19 on the all-cause mortality
among those with HIV (a chronic condition that requires routine care)? Infectious disease epidemiologists and
clinicians are needed to answer urgent COVID-19 questions. The NA-ACCORD will support co-investigators
and their analytic teams, provide the infrastructure to share information, and examine the heterogeneity in
answering these COVID-19 questions investigated expeditiously in 5 existing and new cohorts.

## Key facts

- **NIH application ID:** 10156834
- **Project number:** 3U01AI069918-14S1
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** Keri Nicole Althoff
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $152,652
- **Award type:** 3
- **Project period:** 2020-05-20 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10156834

## Citation

> US National Institutes of Health, RePORTER application 10156834, NA-ACCORD COVID-19 Supplment (3U01AI069918-14S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10156834. Licensed CC0.

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