# Wake Forest ADCC Administrative Supplement

> **NIH NIH P30** · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2020 · $152,153

## Abstract

PROJECT SUMMARY
This administrative supplement is proposed to fund the development of a cognitive battery
based on the UDSv3 that can be administered by telephone or videoconference, and to provide
preliminary feasibility and validation data to inform a future inter-ADRC validation study. The
proposed supplement will be conducted in the Clinical Core cohort of the Alzheimer’s Disease
Research Center (ADRC) at Wake Forest School of Medicine, and falls within the scope of the
ADRC’s aims to provide in-depth clinical and cognitive characterization of this cohort. The
proposal is based on evidence that telephone administration of cognitive tests and
questionnaires is a practical, feasible approach that has been used successfully in other
studies. Several batteries have been validated for phone use in a variety of populations,
including older adults and those with mild cognitive impairment and dementia. However, a
validated a telephone version of the new UDSv3 battery does not exist; alternative methods of
ADRC data collection that yield valid information are needed. Our proposed supplement will lay
critical groundwork for this endeavor. This project seeks to construct two brief adapted
assessment batteries, a Core Battery and an Expanded Battery, that include portions of the in-
person UDSv3 battery that can be administered remotely by telephone and video. We plan to
administer remote assessments to 96 participants from the Wake Forest ADRC who have
undergone in-person follow-up visits within the past six months. Participants will be assigned to
telephone or video administration modalities, and each group will include participants previously
adjudicated as having normal cognition, MCI, and Dementia. Participant ratings of acceptability,
hearing quality, fatigue, and pleasantness of experience (compared to their past recollection of
face-to-face experience) will be assessed using Likert-scale questionnaires for each condition.
Qualitative assessment of what they liked and disliked will also be conducted. Total
administration time, data completeness, refusal of a condition (telephone or video), or refusal to
complete each test will be recorded. Participants’ cognitive status (normal, MCI or dementia) will
be adjudicated using identical procedures to their face-to-face administrations, but adjudicators
will be blinded to original adjudication status. We will also examine whether the associations
among tests across cognitive domains vary by assessment mode. Agreements in adjudications
will also be explored. Lastly, we will convene a group of experts in consultation with the NIA and
the ADRC Clinical Task Force to develop plans for thorough psychometric validation of the
batteries in conjunction with other ADRCs.

## Key facts

- **NIH application ID:** 10158830
- **Project number:** 3P30AG049638-05S1
- **Recipient organization:** WAKE FOREST UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** SUZANNE CRAFT
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $152,153
- **Award type:** 3
- **Project period:** 2016-09-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10158830

## Citation

> US National Institutes of Health, RePORTER application 10158830, Wake Forest ADCC Administrative Supplement (3P30AG049638-05S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10158830. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*