# ITM 2.0: Advancing Translational Science in Metropolitan Chicago

> **NIH NIH UL1** · UNIVERSITY OF CHICAGO · 2020 · $214,196

## Abstract

ABSTRACT
ITM 2.0: ADVANCING TRANSLATIONAL SCIENCE IN METROPOLITAN CHICAGO
The University of Chicago (UChicago) Institute for Translational Medicine (ITM) was created in 2007 to
assemble, integrate, and create the intellectual, administrative, and physical resources required to catalyze
research and research training in Clinical and Translational Science. We have trained university scientists and
health care providers to work together with stakeholders in all concerned communities to determine the
molecular, genetic, pathophysiologic, and social determinants of disease; to develop and test interventions
directed toward those mechanisms; and to achieve these goals in a way that is rigorous, efficient, ethical,
respectful of, and responsive to our community’s needs and values. In its first 9 years, the ITM has capitalized
on outstanding intellectual and physical resources throughout UChicago and at ITM affiliate institutions – Rush
University Medical Center (Rush), NorthShore University HealthSystem (NorthShore), and Illinois Institute of
Technology (IIT) – to build the infrastructure for a transformative, energized, and self-improving home for
clinical and translational research. Now, we pursue a bold guiding vision for “ITM 2.0” – that health outcomes
will be improved throughout Chicagoland by mitigating disease risk, morbidity and mortality through
collaborative, multidisciplinary team science. We will work toward this vision by assembling scientific,
institutional, and community stakeholders, and together focusing on the highest value propositions to improve
mutually defined health concerns, leveraging synergies that accelerate progress across the translational
spectrum. Our core conviction is that participating in health research is a matter of shared self-interest and
social justice, a “new normal” prevailing viewpoint toward which we will strive together over the next 20 years.
ITM 2.0 will work hand-in-hand with health stakeholders throughout Chicagoland and throughout the nation,
conceptualizing, developing and deploying innovative processes and practices to achieve our common goal.
Preparing for this ambitious challenge, we broadened the scope of institutional and community stakeholders.
Rush now joins UChicago as an ITM lead institution, and Loyola University Medical Center and Advocate
Health Care join as ITM affiliates. We partner with esteemed institutions – the Chicago Community Trust, the
Illinois Biotechnology Industry Organization, and the Chicago and Illinois Departments of Public Health – and
inclusively leverage strong collaborations with the other two Chicago CTSAs, with the Chicago-wide PCORnet
CDRN CAPriCORN, and with the recently awarded Illinois Precision Medicine Consortium. In ITM 2.0, we will
together develop innovative and sometimes disruptive approaches to advance the science and practice of
clinical and translational research by rigorously determining which approaches work and then disseminating
the results of both su...

## Key facts

- **NIH application ID:** 10158840
- **Project number:** 3UL1TR002389-04S1
- **Recipient organization:** UNIVERSITY OF CHICAGO
- **Principal Investigator:** Joshua J Jacobs
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $214,196
- **Award type:** 3
- **Project period:** 2017-09-06 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10158840

## Citation

> US National Institutes of Health, RePORTER application 10158840, ITM 2.0: Advancing Translational Science in Metropolitan Chicago (3UL1TR002389-04S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10158840. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*