# Translational Alcohol Research Program (TARP)

> **NIH NIH T32** · YALE UNIVERSITY · 2021 · $451,656

## Abstract

The goal of the Translational Alcohol Research Program (TARP) is to facilitate the ability of
emerging post-doctoral researchers to bridge the gap in the application of knowledge gained from
basic to clinical and social behavioral science research in alcohol use disorders (AUD) and alcohol-
related liver disease (ALD). Both AUD and ALD are major public health problems and they should be
considered together in the diagnosis and management of alcohol abuse and alcoholism. There is a gap
in the application of knowledge f rom basic science studies to clinical models. This is particularly
concerning given the establishment of a new generation of approaches (e.g., genomic, whole-body
imaging) that allow the application of a `systems' approach to the study of AUD and ALD. It is of critical
importance that future investigators are able to exploit these new research tools and approaches to
accelerate the discovery and development of new treatments for ALD and AUD. The TARP is designed to
improve clinical treatment of AUD and ALD by increasing the availability of appropriately-trained young
scientists who are conversant in basic and clinical sciences and able to comfortably traverse the
translational gap between these sciences. It is a two-year program offered by the Yale Schools of
Medicine and Public Health and provides six post-doctoral trainees the opportunity to devote full-time
effort during the initial phase of their careers to developing the skills and experience needed to become
independent researchers in the field of translational research in AUD and ALD. The TARP has four main
“content areas” viz. Reward Mechanisms; Stress and Negative Affect; Comorbidity (psychiatric and
medical); and Alcoholic Liver Disease. The affiliation of TARP faculty with the NIAAA-funded Center for
the Translational Neuroscience of Alcoholism and/or the Yale Liver Center enables the TARP trainees to
conduct research that readily gravitates between preclinical projects (“bench”) and clinical and population
health studies (“bedside” and “community”). Applicants will be MD or PhD post-doctoral candidates,
trained in specialties including psychiatry, internal medicine, clinical psychology, public health,
epidemiology, pharmacology, toxicology, or neuroscience. The TARP includes: 1) individualized, team-
mentored research training, which includes successful completion of a translational-research project, 2) a
core curriculum, including seminars on preclinical and clinical research and treatment, the medical
consequences of excessive alcohol consumption, hepatology, metabolomics, biostatistics, responsible
conduct of scientific research, and grant writing, 3) an individualized training and development plan
(including participation in seminars of interest in associated departments and centers), 4) clinical and/or
basic science training, and 5) training in effective communication and teaching. Upon completion, TARP
graduates will be equipped to establish independent careers in ...

## Key facts

- **NIH application ID:** 10159175
- **Project number:** 5T32AA028259-02
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** Kelly P. Cosgrove
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $451,656
- **Award type:** 5
- **Project period:** 2020-05-01 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10159175

## Citation

> US National Institutes of Health, RePORTER application 10159175, Translational Alcohol Research Program (TARP) (5T32AA028259-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10159175. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*