# Health Informatics to Model the Scott County HIV Outbreak

> **NIH NIH R21** · UNIVERSITY OF GEORGIA · 2020 · $142,338

## Abstract

ABSTRACT
COVID-19 cases and deaths are surging in rural areas of the United States. In the last two weeks of April
2020, the average number of COVID-19 cases per 100,000 persons rose 125% in rural U.S. counties but only
68% in urban counties. During this same time period, COVID-19 related deaths rose 169% in rural areas
compared to 113% in urban areas. As of May 4 2020, Georgia had 28,945 confirmed cases of COVID-19 and
1,186 COVID-19-related deaths. Georgia is a predominantly rural state. Rural people living with HIV (PLHIV)
are at-risk for COVID-19 due, in part, to compromised immune systems and high rates of comorbid health
conditions. Rural PLHIV with comorbid substance use disorders (SUDs) are at particularly high risk for COVID-
19 infection. Many rural PLHIV + SUDs lack access to medical and psychological care, must travel vast
distances to receive HIV and SUD treatments, experience high rates of mood disorders, and experience
discrimination, prejudice, and stigma related to their HIV-status, sexual-identity, and SUD. Georgia is an
opportune state in which to study risk for COVID-19 in rural PLHIV + SUDs. In 2017, Georgia had the highest
HIV prevalence rate per 100,000 residents of any state. Currently, Georgia ranks 12th in number of COVID-19
cases, 5th in hospitalizations due to COVID-19, but has the nation's 7th slowest COVID-19 testing rate. This
study's scientific premise is that, to date, most COVID-19 research has been conducted in urban centers; little
is known about (i) rates of COVID-19 in rural PLHIV + SUDs, (ii) factors predictive of COVID-19 infection in this
group, and (iii) types of preventive behaviors in which rural PLHIV + SUDs engage to avoid infection. This
study will assemble a prospective longitudinal cohort of 100 rural PLHIV in northeast Georgia, 50% of whom
have an active SUD (most likely opioid use disorders). The study will be conducted in Georgia's Health District
10, in which all ten counties are classified as “rural,” 9 are mental health professional shortage areas, and 8
are primary care professional shortage areas. To maximize participant safety, all data will be collected using
innovative remote assessment methodologies. Guided by Wilson and Cleary's model of life quality, participants
will complete assessments at baseline and 3-, 6- and 9-month follow-up that collect: (1) biologic data: CD4
count, HIV viral load, viral hepatitis status; (2) behavioral/psychosocial data: tobacco and marijuana use, vaping
practices, depressive symptoms, ways of coping with COVID-19-related stress, and coping self-efficacy; and
(3) environmental data: housing status and correctional systems involvement. Surveys will also assess
COVID-19 prevention behavior data (e.g., washing hands with soap and water; social distancing). Analyses
will compare rural PLHIV + SUDs to rural PLHIV without SUDs on rates of engaging in COVID-19 preventive
behaviors. Logistic regression analyses will identify factors predictive of COVID-19 infection...

## Key facts

- **NIH application ID:** 10159673
- **Project number:** 3R21DA047893-01A1S1
- **Recipient organization:** UNIVERSITY OF GEORGIA
- **Principal Investigator:** Timothy Glenn Heckman
- **Activity code:** R21 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $142,338
- **Award type:** 3
- **Project period:** 2019-09-30 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10159673

## Citation

> US National Institutes of Health, RePORTER application 10159673, Health Informatics to Model the Scott County HIV Outbreak (3R21DA047893-01A1S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10159673. Licensed CC0.

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