# Yunnan-ADARC HIV Prevention Program: Developing and Testing a Model to Implement and Sustain PrEP Delivery in China.

> **NIH NIH R01** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2021 · $684,644

## Abstract

7. Project Abstract
Pre-exposure prophylaxis (PrEP), a key biomedical HIV prevention strategy, can significantly
reduce HIV incidence in real-world settings. However, introduction and global scale-up of PrEP
have been slow. Part of the challenge is that PrEP is typically introduced into existing health
systems through a hit-or-miss process that is rarely studied. We propose the Yunnan-ADARC
HIV Prevention Program, an implementation science study of the process of introduction and
implementation of PrEP in a specific international health system facing high rates of HIV incidence
among men who have sex with men. YAHPP will introduce and evaluate the implementation of
PrEP among over 1000 men who have sex with men, in eight municipalities in Yunnan, China
utilizing tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) donated by Gilead Sciences. The
study is guided by the Stages of Implementation Completion Framework (SIC) and will use SIC-
associated assessment tools to measure progression across eight pre-defined stages of
implementation, including documenting costs and required resources. YAHPP has two specific
aims: 1) To evaluate whether the addition of Enhanced implementation strategies to Standard
health system PrEP delivery improves client-services outcomes; 2) To compare the time, costs,
and resources required for Standard versus Enhanced PrEP implementation. Enhanced PrEP
implementation will rely on a centralized technical assistance strategy to deliver PrEP-related
knowledge, skills, and best practices to clinics delivering PrEP. The outcome of the study will be
an implementation blueprint that may be used across China and in other low- and middle-income
countries to guide the introduction of PrEP into existing health systems.

## Key facts

- **NIH application ID:** 10159965
- **Project number:** 5R01MH119884-04
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Kathrine Meyers
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $684,644
- **Award type:** 5
- **Project period:** 2019-06-21 → 2023-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10159965

## Citation

> US National Institutes of Health, RePORTER application 10159965, Yunnan-ADARC HIV Prevention Program: Developing and Testing a Model to Implement and Sustain PrEP Delivery in China. (5R01MH119884-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10159965. Licensed CC0.

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