# Microscopy Shared Resource

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2021 · $203,795

## Abstract

MICROSCOPY SHARED RESOURCE ABSTRACT
Cancer research encompasses a broad range of investigations ranging from the behavior of cancer cells in the
body, to the changes in cancer cells at the molecular level. This requires a spectrum of tools that enable
imaging individual cells and their interactions, both at the level of the whole animal, as well as at the molecular
level of molecules inside the cells. The Microscopy Shared Resource (MSR) provides training, access, support
and expertise that enable Moores Cancer Center (MCC) members to successfully utilize basic and advanced
microscopy techniques and instrumentation in their studies. The MSR facility is open 24 hours/7 days per week
and provides access to a wide array of microscopy instrumentation, auxiliary equipment and reagents. The
MSR is pivotal in providing investigators access and expertise to high-end instruments for their studies that
they could not afford otherwise. These instruments include regular epi-fluorescence, bright field and phase
contrast microscopy, confocal, super resolution, Forster Resonance Energy Transfer (FRET), total internal
reflection fluorescence (TIRF), and deconvolution on fixed samples and live cells. The IVIS 200 imaging
system can be used for 3-dimensional optical imaging and non-invasive monitoring of cancer progression,
gene expression patterns, cell trafficking, drug delivery and treatment in living animals. Researchers can use
super resolution fluorescence to examine interactions between proteins and other molecules using
excitation/deactivation of photo-switchable fluorescent probes. The MSR staff provides highly qualified didactic
and hands on training in basic microscopy principles in addition to complex techniques. By bringing together
investigators with diverse interests and common goals, the MSR fosters a spirit of collaboration and
cooperation that leads us closer to the ultimate goals of cancer treatment and cure.

## Key facts

- **NIH application ID:** 10160792
- **Project number:** 5P30CA023100-35
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** David J Hall
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $203,795
- **Award type:** 5
- **Project period:** 1996-07-01 → 2024-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10160792

## Citation

> US National Institutes of Health, RePORTER application 10160792, Microscopy Shared Resource (5P30CA023100-35). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10160792. Licensed CC0.

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